[HTML][HTML] Biomarkers in long COVID-19: A systematic review

YJ Lai, SH Liu, S Manachevakul, TA Lee… - Frontiers in …, 2023 - frontiersin.org
Purpose Long COVID, also known as post-acute sequelae of COVID-19, refers to the
constellation of long-term symptoms experienced by people suffering persistent symptoms …

COVID‐19 immunopathology: from acute diseases to chronic sequelae

M Arish, W Qian, H Narasimhan… - Journal of medical …, 2023 - Wiley Online Library
The clinical manifestation of coronavirus disease 2019 (COVID‐19) mainly targets the lung
as a primary affected organ, which is also a critical site of immune cell activation by severe …

Regulatory T cells (Tregs) and COVID-19: unveiling the mechanisms, and therapeutic potentialities with a special focus on long COVID

M Dhawan, AA Rabaan, S Alwarthan, M Alhajri… - Vaccines, 2023 - mdpi.com
The COVID-19 pandemic has caused havoc all around the world. The causative agent of
COVID-19 is the novel form of the coronavirus (CoV) named SARS-CoV-2, which results in …

Severity of SARS-CoV-2 infection is associated with high numbers of alveolar mast cells and their degranulation

O Krysko, JH Bourne, E Kondakova… - Frontiers in …, 2022 - frontiersin.org
Background The systemic inflammatory response post-SARS-CoV-2 infection increases pro-
inflammatory cytokine production, multi-organ damage, and mortality rates. Mast cells (MC) …

[HTML][HTML] Microvascular significance of TGF-β axis activation in COVID-19

LM Arguinchona, C Zagona-Prizio, ME Joyce… - Frontiers in …, 2023 - frontiersin.org
As 2023 approaches, the COVID-19 pandemic has killed millions. While vaccines have
been a crucial intervention, only a few effective medications exist for prevention and …

The Dynamic Role of FOXP3+ Tregs and Their Potential Therapeutic Applications During SARS-CoV-2 Infection

Z Xu, X Jiang, X Dai, B Li - Frontiers in immunology, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19) has been raging all around the world since the
beginning of 2020, and leads to acute respiratory distress syndrome (ARDS) with strong …

How do anti-SARS-CoV-2 mRNA vaccines protect from severe disease?

M Federico - International Journal of Molecular Sciences, 2022 - mdpi.com
COVID-19 pathogenesis develops in two phases. First, Severe Acute Respiratory Syndrome
Coronavirus (SARS-CoV)-2 spreads within the epithelial cells of the mucosa of upper and …

[HTML][HTML] Therapeutic potential of green tea catechin,(-)-epigallocatechin-3-O-gallate (EGCG) in SARS-CoV-2 infection: Major interactions with host/virus proteases

B Dinda, S Dinda, M Dinda - Phytomedicine Plus, 2023 - Elsevier
Background The current COVID-19 pandemic from the human pathogenic virus SARS-CoV-
2 has resulted in a major health hazard globally. The morbidity and transmission modality of …

Inflammatory pathways in COVID‐19: Mechanism and therapeutic interventions

Y Jiang, T Zhao, X Zhou, Y Xiang… - MedComm, 2022 - Wiley Online Library
Abstract The 2019 coronavirus disease (COVID‐19) pandemic has become a global crisis.
In the immunopathogenesis of COVID‐19, SARS‐CoV‐2 infection induces an excessive …

Molecular and immune signatures, and pathological trajectories of fatal COVID‐19 lungs defined by in situ spatial single‐cell transcriptome analysis

A Das, W Meng, Z Liu, MM Hasib… - Journal of Medical …, 2023 - Wiley Online Library
Despite intensive studies during the last 3 years, the pathology and underlying molecular
mechanism of coronavirus disease 2019 (COVID‐19) remain poorly defined. In this study …