Successful treatment of solid cancers relies on complete surgical excision of the tumor either
for definitive treatment or before adjuvant therapy. Intraoperative and postoperative radial …

Here, we summarize the literature relevant to recent advances in three‐dimensional (3D)
histopathology in relation to clinical oncology, highlighting serial sectioning, tissue clearing …

Background and objective The automatic registration of differently stained whole slide
images (WSIs) is crucial for improving diagnosis and prognosis by fusing complementary …

Emerging spatial omics technologies continue to advance the molecular mapping of tissue
architecture and the investigation of gene regulation and cellular crosstalk, which in turn …

There is a lack of systematic research exploring cross-species variation in liver lobular
geometry and zonation patterns of critical drug-metabolizing enzymes, a knowledge gap …

Numerous imaging techniques are available for observing and interrogating biological
samples, and several of them can be used consecutively to enable correlative analysis of …

The lack of standardization in antibody validation remains a major contributor to
irreproducibility of human research. To address this, we have applied a standardized …

DeeperHistReg is a software framework dedicated to registering whole slide images (WSIs)
acquired using multiple stains. It allows one to perform the preprocessing, initial alignment …

Thyroid cancer is the most common endocrine malignancy, and accurately distinguishing
between benign and malignant thyroid tumors is crucial for developing effective treatment …

Whole Slide Images (WSIs) provide exceptional detail for studying tissue architecture at the
cell level. To study tumour microenvironment (TME) with the context of various protein …