Nanoparticles in drug delivery: From history to therapeutic applications

O Afzal, ASA Altamimi, MS Nadeem, SI Alzarea… - Nanomaterials, 2022 - mdpi.com
Current research into the role of engineered nanoparticles in drug delivery systems (DDSs)
for medical purposes has developed numerous fascinating nanocarriers. This paper reviews …

Reactive oxygen species (ROS)-based nanomedicine

B Yang, Y Chen, J Shi - Chemical reviews, 2019 - ACS Publications
Reactive oxygen species (ROS) play an essential role in regulating various physiological
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …

ROS-scavenging therapeutic hydrogels for modulation of the inflammatory response

YE Kim, J Kim - ACS Applied Materials & Interfaces, 2021 - ACS Publications
Although reactive oxygen species (ROS) are essential for cellular processes, excessive
ROS could be a major cause of various inflammatory diseases because of the oxidation of …

JCS 2018 guideline on diagnosis and treatment of acute coronary syndrome

K Kimura, T Kimura, M Ishihara, Y Nakagawa… - Circulation …, 2019 - jstage.jst.go.jp
Acute coronary syndromes (ACS) are a comprehensive disease concept characterized by
acute myocardial ischemia caused by disruption of coronary artery plaque and consequent …

Extracellular vesicles in cardiovascular disease: biological functions and therapeutic implications

C Han, J Yang, J Sun, G Qin - Pharmacology & therapeutics, 2022 - Elsevier
Extracellular vesicles (EVs), including exosomes and microvesicles, are lipid bilayer
particles naturally released from the cell. While exosomes are formed as intraluminal …

Targeting ferroptosis against ischemia/reperfusion cardiac injury

J Lillo-Moya, C Rojas-Solé, D Muñoz-Salamanca… - Antioxidants, 2021 - mdpi.com
Ischemic heart disease is a leading cause of death worldwide. Primarily, ischemia causes
decreased oxygen supply, resulting in damage of the cardiac tissue. Naturally …

B lymphocytes trigger monocyte mobilization and impair heart function after acute myocardial infarction

Y Zouggari, H Ait-Oufella, P Bonnin, T Simon… - Nature medicine, 2013 - nature.com
Acute myocardial infarction is a severe ischemic disease responsible for heart failure and
sudden death. Here, we show that after acute myocardial infarction in mice, mature B …

Circulating microRNA: a novel potential biomarker for early diagnosis of acute myocardial infarction in humans

GK Wang, JQ Zhu, JT Zhang, Q Li, Y Li… - European heart …, 2010 - academic.oup.com
Aims microRNA (miRNA) is reported to be present in the blood of humans and has been
increasingly suggested as a biomarker for diseases. We aim to determine the potential of …

Challenges in secondary prevention after acute myocardial infarction: A call for action

MF Piepoli, U Corrà, P Dendale… - European journal of …, 2017 - academic.oup.com
Worldwide, each year more than 7 million people experience myocardial infarction, in which
one-year mortality rates are now in the range of 10%, but vary with patient characteristics …

Predicting diagnostic gene biomarkers associated with immune infiltration in patients with acute myocardial infarction

E Zhao, H Xie, Y Zhang - Frontiers in Cardiovascular Medicine, 2020 - frontiersin.org
Objective: The present study was designed to identify potential diagnostic markers for acute
myocardial infarction (AMI) and determine the significance of immune cell infiltration in this …