Pre-extinction administration of Δ 9-tetrahydrocannibinol (THC) facilitates recall of extinction
in healthy humans, and evidence from animal studies suggest that this likely occurs via …

Although exposure to major psychological trauma is unfortunately common, risk for related
neuropsychiatric conditions, such as post-traumatic stress disorder (PTSD), varies greatly …

Addiction remains a major public health concern, and while pharmacotherapies can be
effective, clinicians are limited by the paucity of existing interventions. Endocannabinoid …

Research over the past few decades has established a role for the endocannabinoid system
in contributing to the neural and endocrine responses to stress exposure. The two …

The endocannabinoid system has been implicated in the regulation of the stress response,
fear memory formation, and inflammatory processes. Posttraumatic stress disorder (PTSD) …

Preclinical research suggests that enhancing CB1 receptor agonism may improve fear
extinction. In order to translate this knowledge into a clinical application we examined …

Mental disorders have a high prevalence compared with many other health conditions and
are the leading cause of disability worldwide. Several studies performed in the last years …

A novel strategy to treat anxiety and fear-related disorders such as phobias, panic and PTSD
(post-traumatic stress disorder) is combining CBT (cognitive behavioural therapy), including …

The objective of this review is to point out some important facts that we don't know about
endogenous cannabinoids—lipid-derived signaling molecules that activate CB 1 …

The endocannabinoid signaling system (ECSS) is altered by exposure to stress and
mediates and modulates the effects of stress on the brain. Considerable preclinical data …