Disentangling the relative importance of T cell responses in COVID-19: leading actors or supporting cast?
The rapid development of multiple vaccines providing strong protection from severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been a major achievement …
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been a major achievement …
Evolution of immune responses to SARS-CoV-2 in mild-moderate COVID-19
The durability of infection-induced SARS-CoV-2 immunity has major implications for
reinfection and vaccine development. Here, we show a comprehensive profile of antibody, B …
reinfection and vaccine development. Here, we show a comprehensive profile of antibody, B …
[HTML][HTML] Functional SARS-CoV-2-specific immune memory persists after mild COVID-19
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus is causing a
global pandemic, and cases continue to rise. Most infected individuals experience mildly …
global pandemic, and cases continue to rise. Most infected individuals experience mildly …
Prospects for durable immune control of SARS-CoV-2 and prevention of reinfection
Immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is
central to long-term control of the current pandemic. Despite our rapidly advancing …
central to long-term control of the current pandemic. Despite our rapidly advancing …
[HTML][HTML] Antigen-specific adaptive immunity to SARS-CoV-2 in acute COVID-19 and associations with age and disease severity
Limited knowledge is available on the relationship between antigen-specific immune
responses and COVID-19 disease severity. We completed a combined examination of all …
responses and COVID-19 disease severity. We completed a combined examination of all …
[HTML][HTML] Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19
T Sekine, A Perez-Potti, O Rivera-Ballesteros, K Strålin… - Cell, 2020 - cell.com
Summary SARS-CoV-2-specific memory T cells will likely prove critical for long-term immune
protection against COVID-19. Here, we systematically mapped the functional and …
protection against COVID-19. Here, we systematically mapped the functional and …
Long-term perturbation of the peripheral immune system months after SARS-CoV-2 infection
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly
infectious respiratory virus which is responsible for the coronavirus disease 2019 (COVID …
infectious respiratory virus which is responsible for the coronavirus disease 2019 (COVID …
COVID-19 vaccine frontrunners and their nanotechnology design
YH Chung, V Beiss, SN Fiering, NF Steinmetz - ACS nano, 2020 - ACS Publications
Humanity is experiencing a catastrophic pandemic. SARS-CoV-2 has spread globally to
cause significant morbidity and mortality, and there still remain unknowns about the biology …
cause significant morbidity and mortality, and there still remain unknowns about the biology …
SARS-CoV-2 mRNA vaccines foster potent antigen-specific germinal center responses associated with neutralizing antibody generation
The deployment of effective vaccines against severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is critical to eradicate the coronavirus disease 2019 (COVID …
coronavirus 2 (SARS-CoV-2) is critical to eradicate the coronavirus disease 2019 (COVID …
Characterization of pre-existing and induced SARS-CoV-2-specific CD8+ T cells
I Schulien, J Kemming, V Oberhardt, K Wild… - Nature medicine, 2021 - nature.com
Emerging data indicate that SARS-CoV-2-specific CD8+ T cells targeting different viral
proteins are detectable in up to 70% of convalescent individuals,,,–. However, very little …
proteins are detectable in up to 70% of convalescent individuals,,,–. However, very little …