Inactivated whole-virion vaccine BBV152/Covaxin elicits robust cellular immune memory to SARS-CoV-2 and variants of concern

R Vikkurthi, A Ansari, AR Pai, SN Jha, S Sachan… - Nature …, 2022 - nature.com
BBV152 is a whole-virion inactivated vaccine based on the Asp614Gly variant. BBV152 is
the first alum-imidazoquinolin-adjuvanted vaccine authorized for use in large populations …

A single-dose mRNA vaccine provides a long-term protection for hACE2 transgenic mice from SARS-CoV-2

Q Huang, K Ji, S Tian, F Wang, B Huang, Z Tong… - Nature …, 2021 - nature.com
The rapid expansion of the COVID-19 pandemic has made the development of a SARS-CoV-
2 vaccine a global health and economic priority. Taking advantage of versatility and rapid …

The role of immune activation and antigen persistence in acute and long COVID

S Opsteen, JK Files, T Fram… - Journal of Investigative …, 2023 - journals.sagepub.com
In late 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) triggered the
global coronavirus disease 2019 (COVID-19) pandemic. Although most infections cause a …

Expert review on global real-world vaccine effectiveness against SARS-CoV-2

S Chuenkitmongkol, R Solante, E Burhan… - Expert review of …, 2022 - Taylor & Francis
Introduction COVID-19 vaccines have been highly effective in reducing morbidity and
mortality during the pandemic. While primary series vaccination rates are generally high in …

T cells in COVID-19—united in diversity

L Swadling, MK Maini - Nature immunology, 2020 - nature.com
T cells in COVID-19 — united in diversity | Nature Immunology Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

The T-cell response to SARS-CoV-2: kinetic and quantitative aspects and the case for their protective role

A Bertoletti, AT Tan, N Le Bert - Oxford Open Immunology, 2021 - academic.oup.com
Abstract Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2), the etiological
agent of Coronavirus Diseases 2019 (COVID-19), triggers an adaptive immunity in the …

Testing fractional doses of COVID-19 vaccines

W Więcek, A Ahuja, E Chaudhuri… - Proceedings of the …, 2022 - National Acad Sciences
Due to the enormous economic, health, and social costs of the COVID-19 pandemic, there
are high expected social returns to investing in parallel in multiple approaches to …

Decay of Fc-dependent antibody functions after mild to moderate COVID-19

WS Lee, KJ Selva, SK Davis, BD Wines, A Reynaldi… - Cell Reports …, 2021 - cell.com
The capacity of antibodies to engage with immune cells via the Fc region is important in
preventing and controlling many infectious diseases. The evolution of such antibodies …

Mapping the SARS-CoV-2 spike glycoprotein-derived peptidome presented by HLA class II on dendritic cells

R Parker, T Partridge, C Wormald, R Kawahara… - Cell reports, 2021 - cell.com
Understanding and eliciting protective immune responses to severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) is an urgent priority. To facilitate these objectives …

T cell perturbations persist for at least 6 months following hospitalization for COVID-19

M Govender, FR Hopkins, R Göransson… - Frontiers in …, 2022 - frontiersin.org
COVID-19 is being extensively studied, and much remains unknown regarding the long-term
consequences of the disease on immune cells. The different arms of the immune system are …