As common mental disorders, depression and anxiety impact people all around the world.
Recent studies have found that the gut microbiome plays an important role in mental health …

Alterations in glutamatergic and GABAergic function in the medial prefrontal cortex (mPFC)
are prevalent in individuals with major depressive disorder, resulting in impaired synaptic …

Stroke is one of the leading causes of death and disability in the world, of which ischemia
accounts for the majority. There is growing evidence of changes in synaptic connections and …

Major depressive disorder (MDD) is a devastating mental disorder that affects up to 17% of
the population worldwide. Although brain-wide network-level abnormalities in MDD patients …

Adolescence is a time of significant neurocognitive development. Prolonged maturation of
prefrontal cortex (PFC) through adolescence has been found to support improvements in …

Stress-related psychiatric disorders and the stress system show prominent differences
between males and females, as well as strongly divergent transcriptional changes. Despite …

Psychedelic compounds have shown extraordinary potential in treating a wide range of
neuropsychiatric disorders. Psilocybin, for example, has now been shown in several clinical …

Major depressive disorder (MDD or depression) is a debilitating neuropsychiatric syndrome
with genetic, epigenetic, and environmental contributions. Depression is one of the largest …

Mitochondrial dysfunction was highlighted as a crucial vulnerability factor for the
development of depression. However, systemic studies assessing stress-induced changes …

Major depressive disorder (MDD) presents different clinical features in women and men,
with women being more affected and responding differently to antidepressant treatment …