The Escherichia coli gene purF, coding for 5-phosphoribosylamine: glutamine
pyrophosphate phosphoribosyltransferase (amidophosphoribosyltransferase) was …

Nitrogen is incorporated into various metabolites by multifunctional glutamine
amidotransferases via reactive ammonia generated by glutaminase hydrolysis of glutamine …

Saccharomyces cerevisiae gene ADE4 encoding glutamine phosphoribosylpyrophosphate
amidotransferase (amidophosphoribosyltransferase) has been cloned by complementation …

In human cells, de novo purine nucleotide biosynthesis is known to be regulated through the
formation of a metabolon called purinosome. Here, we employed a bacterial two‐hybrid …

The Escherichia coli asparagine synthetase B gene (asnB) has been cloned into a
temperature-sensitive, low copy plasmid, pOU71, as shown by the complementation of an E …

We demonstrate here that Escherichia coli synthesizes two different glycinamide
ribonucleotide (GAR) transformylases, both catalyzing the third step in the purine …

In order to test a possible approach to enhance fermentative inosine production by Bacillus
subtilis, seven gene-targeted mutations were introduced in the laboratory standard strain168 …

De novo purine nucleotide synthesis is regulated, at least in part, by end-product inhibition
of glutamine PRPP amidotransferase. An important feature of this inhibition is the fact that …

Escherichia coli asparagine synthetase B (AS-B) catalyzes the formation of asparagine from
aspartate in an ATP-dependent reaction for which glutamine is the in vivo nitrogen source. In …

The Bacillus subtilis pur operon is a 12-gene cluster, purEKB-purC (orf) QLF-purMNH (J)-
purD, organized in groups of overlapping coding units separated by intercistronic gaps …