Currently there is a lack of randomized trial data examining the use of the antiviral nirmatrelvir/ritonavir in paediatric patients with SARS-CoV-2 infection. This target trial …
In a pivotal trial, a 5-day course of oral ritonavir-boosted nirmatrelvir decreased hospitalization and death by 89.1% and reduced nasal viral load by 0.87 log relative to …
S Esmaeili, K Owens, J Wagoner, SJ Polyak, JM White… - medRxiv, 2024 - ncbi.nlm.nih.gov
In a pivotal trial (EPIC-HR), a 5-day course of oral ritonavir-boosted nirmatrelvir, given early during symptomatic SARS-CoV-2 infection (within three days of symptoms onset) …