High comorbidity, measured by the Charlson Comorbidity Index, associates with higher 1-year mortality risks in elderly patients experiencing a first acute heart failure …

F Formiga, R Moreno-Gonzalez, D Chivite… - Aging Clinical and …, 2018 - Springer
Background Comorbidity is related to poor health results in chronic heart failure (HF). Aims
The purpose of the study was to assess whether a high Charlson Comorbidity Index score …

Low serum albumin is associated with mortality and arterial and venous ischemic events in acutely ill medical patients. Results of a retrospective observational study

F Violi, A Novella, P Pignatelli, V Castellani… - Thrombosis …, 2023 - Elsevier
Background In general population hypoalbuminemia is associated with poor survival. Aim of
this study was to assess the impact of hypoalbuminemia on mortality and venous and …

Polypharmacy and the risk of drug–drug interactions and potentially inappropriate medications in hospital psychiatry

J Wolff, G Hefner, C Normann, K Kaier… - … and Drug Safety, 2021 - Wiley Online Library
Purpose The aim of this study was to analyze the epidemiology of polypharmacy in hospital
psychiatry. Another aim was to investigate predictors of the number of drugs taken and the …

Adherence to antithrombotic therapy guidelines improves mortality among elderly patients with atrial fibrillation: insights from the REPOSI study

M Proietti, A Nobili, V Raparelli, L Napoleone… - Clinical Research in …, 2016 - Springer
Background Atrial fibrillation (AF) is associated with a substantial risk of thromboembolism
and mortality, significantly reduced by oral anticoagulation. Adherence to guidelines may …

Is polypharmacy an independent risk factor for adverse outcomes after an emergency department visit?

F Salvi, L Rossi, F Lattanzio, A Cherubini - Internal and emergency …, 2017 - Springer
This study aimed at verifying the role of polypharmacy as an independent risk factor for
adverse health outcomes in older emergency department (ED) patients. This was a large (n …

Potentially inappropriate medications, drug–drug interactions, and anticholinergic burden in elderly hospitalized patients: does an association exist with post …

A De Vincentis, P Gallo, P Finamore, C Pedone… - Drugs & Aging, 2020 - Springer
Background Polypharmacy is very common in elderly patients and is associated with
detrimental outcomes. Objective Our objective was to evaluate the associations between a …

Knowledge and willingness of physicians about deprescribing among older patients: a qualitative study

MM Alrasheed, TM Alhawassi, A Alanazi… - … interventions in aging, 2018 - Taylor & Francis
Purpose This study aimed to explore the physician's knowledge and identify the perceived
barriers that prevent family medicine physicians from engaging in deprescribing among …

Under-detection of delirium and impact of neurocognitive deficits on in-hospital mortality among acute geriatric and medical wards

G Bellelli, A Nobili, G Annoni, A Morandi… - European Journal of …, 2015 - Elsevier
Background Delirium is a neuropsychiatric disorder, triggered by medical precipitants
causes. Study aims were to describe the prevalence and impact on in-hospital mortality of …

Polypharmacy and potentially inappropriate prescriptions identified by B eers and STOPP criteria in co‐morbid older patients at hospital discharge

K Hudhra, M García‐Caballos… - Journal of evaluation …, 2016 - Wiley Online Library
Rationale, aims and objectives The objective of this study was to evaluate the prevalence of
potentially inappropriate prescriptions (PIP) and the association with polypharmacy (more …

Gender-differences in disease distribution and outcome in hospitalized elderly: data from the REPOSI study

S Corrao, P Santalucia, C Argano, CD Djade… - European journal of …, 2014 - Elsevier
Background and purpose Women live longer and outnumber men. On the other hand, older
women develop more chronic diseases and conditions such as arthritis, osteoporosis and …