[HTML][HTML] Anti-inflammatory and antiviral effects of cannabinoids in inhibiting and preventing SARS-CoV-2 infection

M Janecki, M Graczyk, AA Lewandowska… - International journal of …, 2022 - mdpi.com
The COVID-19 pandemic caused by the SARS-CoV-2 virus made it necessary to search for
new options for both causal treatment and mitigation of its symptoms. Scientists and …

[HTML][HTML] Modulation of pulmonary immune function by inhaled cannabis products and consequences for lung disease

M Preteroti, ET Wilson, DH Eidelman, CJ Baglole - Respiratory Research, 2023 - Springer
The lungs, in addition to participating in gas exchange, represent the first line of defense
against inhaled pathogens and respiratory toxicants. Cells lining the airways and alveoli …

[HTML][HTML] Cannabinoids alleviate the LPS-induced cytokine storm via attenuating NLRP3 inflammasome signaling and TYK2-mediated STAT3 signaling pathways in …

SV Suryavanshi, M Zaiachuk, N Pryimak, I Kovalchuk… - Cells, 2022 - mdpi.com
Cannabinoids, mainly cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC), are the most
studied group of compounds obtained from Cannabis sativa because of their several …

[HTML][HTML] A review of natural products, their effects on SARS-CoV-2 and their utility as lead compounds in the discovery of drugs for the treatment of COVID-19

RL Chapman, SV Andurkar - Medicinal Chemistry Research, 2022 - Springer
During the COVID-19 pandemic lasting now for well more than a year, nearly 247 million
cases have been diagnosed and over 5 million deaths have been recorded worldwide as of …

[HTML][HTML] Anti-microbial activity of phytocannabinoids and endocannabinoids in the light of their physiological and pathophysiological roles

RV Sionov, D Steinberg - Biomedicines, 2022 - mdpi.com
Antibiotic resistance has become an increasing challenge in the treatment of various
infectious diseases, especially those associated with biofilm formation on biotic and abiotic …

[HTML][HTML] Cannabidiol and terpene formulation reducing SARS-CoV-2 infectivity tackling a therapeutic strategy

S Santos, P Barata, A Charmier, I Lehmann… - Frontiers in …, 2022 - frontiersin.org
In late 2019, COVID-19 emerged in Wuhan, China. Currently, it is an ongoing global health
threat stressing the need for therapeutic compounds. Linking the virus life cycle and its …

[HTML][HTML] High-CBD extract (CBD-X) downregulates cytokine storm systemically and locally in inflamed lungs

M Aswad, H Hamza, A Pechkovsky, A Zikrach… - Frontiers in …, 2022 - frontiersin.org
Cytokine storm refers to the dysregulated production of inflammatory mediators leading to
hyperinflammation. They are often detrimental, and worsen the severity of COVID-19 and …

[HTML][HTML] Antimicrobial and Antiviral (SARS-CoV-2) Potential of Cannabinoids and Cannabis sativa: A Comprehensive Review

MS Mahmud, MS Hossain, ATMF Ahmed, MZ Islam… - Molecules, 2021 - mdpi.com
Antimicrobial resistance has emerged as a global health crisis and, therefore, new drug
discovery is a paramount need. Cannabis sativa contains hundreds of chemical constituents …

[HTML][HTML] An overview on the epidemiology and immunology of COVID-19

M Meskini, MR Rami, P Maroofi, S Ghosh… - Journal of Infection and …, 2021 - Elsevier
Coronaviruses are a large family of viruses that cause illnesses ranging from the common
cold to more severe diseases such as Middle East Respiratory Syndrome (MERS), Severe …

Tranilast as an adjunctive therapy in hospitalized patients with severe COVID-19: a randomized controlled trial

A Saeedi-Boroujeni, R Nashibi, AA Ghadiri… - Archives of medical …, 2022 - Elsevier
Background Tranilast is a potential NLRP3 inflammasome inhibitor that may relieve
progressive inflammation due to COVID-19. Aim of the study To evaluate the therapeutic …