Plant‐derived extracellular vesicles: recent advancements and current challenges on their use for biomedical applications

MQ Lian, WH Chng, J Liang, HQ Yeo… - Journal of …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) represent a diverse class of lipid bilayer membrane vesicles
released by both animal and plant cells. These ubiquitous vesicles are involved in …

[HTML][HTML] Plant-derived extracellular vesicles (PDEVs) in nanomedicine for human disease and therapeutic modalities

Z Xu, Y Xu, K Zhang, Y Liu, Q Liang, A Thakur… - Journal of …, 2023 - Springer
Background The past few years have witnessed a significant increase in research related to
plant-derived extracellular vesicles (PDEVs) in biological and medical applications. Using …

Recent insights into the nutritional immunomodulation of cancer‐related microRNAs

TÖ Şahin, B Yılmaz, N Yeşilyurt, D Cicia… - Phytotherapy …, 2023 - Wiley Online Library
Cancer is the most common cause of death worldwide, following cardiovascular diseases.
Cancer is a multifactorial disease and many reasons such as physical, chemical, biological …

[HTML][HTML] Plant-derived exosomes as a drug-delivery approach for the treatment of inflammatory bowel disease and colitis-associated cancer

Y Cai, L Zhang, Y Zhang, R Lu - Pharmaceutics, 2022 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic recurrent intestinal disease and includes
Crohn's disease (CD) and ulcerative colitis (UC). Due to the complex etiology of colitis, the …

[HTML][HTML] Tea leaf-derived exosome-like nanotherapeutics retard breast tumor growth by pro-apoptosis and microbiota modulation

Q Chen, M Zu, H Gong, Y Ma, J Sun, S Ran… - Journal of …, 2023 - Springer
While several artificial nanodrugs have been approved for clinical treatment of breast tumor,
their long-term applications are restricted by unsatisfactory therapeutic outcomes, side …

[HTML][HTML] Novel plant-derived exosome-like nanovesicles from Catharanthus roseus: preparation, characterization, and immunostimulatory effect via TNF-α/NF-κB/PU …

X Ou, H Wang, H Tie, J Liao, Y Luo, W Huang… - Journal of …, 2023 - Springer
Background Plant-derived exosomes-like nanovesicles (PDENs) have been found to be
advantageous in disease treatment and drug delivery, but research on their biogenesis …

Engineering extracellular vesicles as delivery systems in therapeutic applications

L Wang, D Wang, Z Ye, J Xu - Advanced Science, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are transport vesicles secreted by living cells and released into
the extracellular environment. Recent studies have shown that EVs serve as “messengers” …

[HTML][HTML] Plant-derived extracellular vesicles and their exciting potential as the future of next-generation drug delivery

FA Alzahrani, MI Khan, N Kameli, E Alsahafi, YM Riza - Biomolecules, 2023 - mdpi.com
Plant cells release tiny membranous vesicles called extracellular vesicles (EVs), which are
rich in lipids, proteins, nucleic acids, and pharmacologically active compounds. These plant …

[HTML][HTML] Focusing on future applications and current challenges of plant derived extracellular vesicles

Y Wang, J Wang, J Ma, Y Zhou, R Lu - Pharmaceuticals, 2022 - mdpi.com
Plant derived extracellular vesicles (EVs) are nano-sized membranous vesicles released by
plant cells, which contain lipids, proteins, nucleic acids and specific pharmacologically …

[HTML][HTML] Emergence of edible plant-derived nanovesicles as functional food components and nanocarriers for therapeutics delivery: potentials in human health and …

SQ Kim, KH Kim - Cells, 2022 - mdpi.com
Extracellular vesicles (EVs) are a highly heterogeneous population of membranous particles
that are secreted by almost all types of cells across different domains of life, including plants …