MALDI-TOF mass spectrometry in clinical analysis and research

D Li, J Yi, G Han, L Qiao - ACS Measurement Science Au, 2022 - ACS Publications
In the decade after being awarded the Nobel Prize in Chemistry in 2002, matrix-assisted
laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has been …

Advanced on-site and in vitro signal amplification biosensors for biomolecule analysis

Y Wang, B Li, T Tian, Y Liu, J Zhang, K Qian - TrAC Trends in Analytical …, 2022 - Elsevier
Point-of-care testing (POCT), as one part of in vitro diagnostic (IVD), has been gradually
used in early diagnosis and personalized treatment in the clinics. Accurate and sensitive …

Diagnosis and prognosis of breast cancer by high-performance serum metabolic fingerprints

Y Huang, S Du, J Liu, W Huang, W Liu… - Proceedings of the …, 2022 - National Acad Sciences
High-performance metabolic analysis is emerging in the diagnosis and prognosis of breast
cancer (BrCa). Still, advanced tools are in demand to deliver the application potentials of …

Comprehensive metabolic fingerprints characterize neuromyelitis optica spectrum disorder by nanoparticle-enhanced laser desorption/ionization mass spectrometry

W Chen, H Yu, Y Hao, W Liu, R Wang, Y Huang, J Wu… - ACS …, 2023 - ACS Publications
Timely screening of neuromyelitis optica spectrum disorder (NMOSD) and differential
diagnosis from myelin oligodendrocyte glycoprotein associated disorder (MOGAD) are the …

Exosome metabolic patterns on aptamer-coupled polymorphic carbon for precise detection of early gastric cancer

H Chen, C Huang, Y Wu, N Sun, C Deng - ACS nano, 2022 - ACS Publications
Gastric cancer (GC) presents high mortality worldwide because of delayed diagnosis.
Currently, exosome-based liquid biopsy has been applied in diagnosis and monitoring of …

Integrative serum metabolic fingerprints based multi‐modal platforms for lung adenocarcinoma early detection and pulmonary nodule classification

L Wang, M Zhang, X Pan, M Zhao, L Huang… - Advanced …, 2022 - Wiley Online Library
Identification of novel non‐invasive biomarkers is critical for the early diagnosis of lung
adenocarcinoma (LUAD), especially for the accurate classification of pulmonary nodule …

Defective Fe Metal–Organic Frameworks Enhance Metabolic Profiling for High‐Accuracy Diagnosis of Human Cancers

J Yang, X Yin, L Zhang, X Zhang, Y Lin… - Advanced …, 2022 - Wiley Online Library
Cancers heavily threaten human life; therefore, a high‐accuracy diagnosis is vital to protect
human beings from the suffering of cancers. While biopsies and imaging methods are widely …

Serum metabolic fingerprints on bowl-shaped submicroreactor chip for chemotherapy monitoring

X Yin, J Yang, M Zhang, X Wang, W Xu, CAH Price… - ACS …, 2022 - ACS Publications
Chemotherapy is a primary cancer treatment strategy, the monitoring of which is critical to
enhancing the survival rate and quality of life of cancer patients. However, current …

Plasmon-activated NO2 sensor based on Au@ MoS2 core-shell nanoparticles with heightened sensitivity and full recoverability

J Hu, X Liu, J Zhang, X Gu, Y Zhang - Sensors and Actuators B: Chemical, 2023 - Elsevier
Developing high-performance gas-sensing devices based on transition metal
dichalcogenides (TMDs) has sparked significant research interest in efficient detection of …

Designed concave octahedron heterostructures decode distinct metabolic patterns of epithelial ovarian tumors

C Pei, Y Wang, Y Ding, R Li, W Shu, Y Zeng… - Advanced …, 2023 - Wiley Online Library
Epithelial ovarian cancer (EOC) is a polyfactorial process associated with alterations in
metabolic pathways. A high‐performance screening tool for EOC is in high demand to …