Ageing is associated with modified function of both innate and adaptive immunity. It is
believed that changes occurring in ageing immune system are responsible for increased …

The function of the immune system declines during aging, compromising its response
against pathogens, a phenomenon termed as “immunosenescence.” Alterations of the …

The process of aging is accompanied by a dynamic restructuring of the immune response, a
phenomenon known as immunosenescence. This mini-review navigates through the …

Inflammaging and SARS-CoV-2 infection interact in an interplay that involves both acute
inflammation and low-grade chronic inflammation, predisposing older adults to severe …

Advanced age is one of the significant risk determinants for coronavirus disease 2019
(COVID-19)-related mortality and for long COVID complications. The contributing factors …

Parkinson's disease (PD) is the second most prevalent neurodegenerative disease after
Alzheimer's disease, globally. Dopaminergic neuron degeneration in substantia nigra pars …

During the current pandemic, the vast majority of COVID-19 patients experienced mild
symptoms, but some had a potentially fatal aberrant hyperinflammatory immune reaction …

With the progressive lengthening of the average age of the population, especially in some
countries such as Italy, vaccination of the elderly is a fixed point on which most of the public …

Cytomegalovirus (CMV) infection is a major driver of accelerated immunosenescence
related to CD28null T cell expansion. CMV infection and these proatherogenic T cells have …

Mycobacterium tuberculosis (M. tb) and SARS-CoV-2 are both infections that can lead to
severe disease in the lower lung. However, these two infections are caused by very different …