Neuroinflammation in Alzheimer's disease

IG Onyango, GV Jauregui, M Čarná, JP Bennett Jr… - Biomedicines, 2021 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disease associated with human aging.
Ten percent of individuals over 65 years have AD and its prevalence continues to rise with …

Neuroprotective effects of flavone luteolin in neuroinflammation and neurotrauma

D Kempuraj, R Thangavel, DD Kempuraj… - Biofactors, 2021 - Wiley Online Library
Neuroinflammation leads to neurodegeneration, cognitive defects, and neurodegenerative
disorders. Neurotrauma/traumatic brain injury (TBI) can cause activation of glial cells …

Role of SARS-CoV-2 spike-protein-induced activation of microglia and mast cells in the pathogenesis of neuro-COVID

TC Theoharides, D Kempuraj - Cells, 2023 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19). About 45% of COVID-19 patients experience several symptoms a …

Naringenin: A prospective therapeutic agent for Alzheimer's and Parkinson's disease

A Goyal, A Verma, N Dubey, J Raghav… - Journal of Food …, 2022 - Wiley Online Library
Neurodegenerative disorders (NDs) are a cluster of progressive, severe, and disabling
disorders that affect millions of people worldwide and are on the surge. These disorders are …

New frontiers in the prevention, diagnosis, and treatment of Alzheimer's disease

L Guzman-Martinez, C Calfío, GA Farias… - Journal of …, 2021 - content.iospress.com
One of the major puzzles in medical research and public health systems worldwide is
Alzheimer's disease (AD), reaching nowadays a prevalence near 50 million people. This is a …

Medicine–food herb: Angelica sinensis, a potential therapeutic hope for Alzheimer's disease and related complications

Y Long, D Li, S Yu, A Shi, J Deng, J Wen, X Li, Y Ma… - Food & Function, 2022 - pubs.rsc.org
Alzheimer's disease (AD) is a progressive neurodegenerative disease, which has brought a
huge burden to the world. The current therapeutic approach of one-molecule-one-target …

Recent trends and practices toward assessment and rehabilitation of neurodegenerative disorders: Insights from human gait

R Das, S Paul, GK Mourya, N Kumar… - Frontiers in …, 2022 - frontiersin.org
The study of human movement and biomechanics forms an integral part of various clinical
assessments and provides valuable information toward diagnosing neurodegenerative …

Novel nutraceutical compounds in Alzheimer prevention

RB Maccioni, C Calfío, A González, V Lüttges - Biomolecules, 2022 - mdpi.com
Alzheimer's disease (AD) incidence is increasing worldwide at an alarming rate.
Considering this increase, prevention efforts, stemming from scientific research, health …

Challenges in the development of drug delivery systems based on small extracellular vesicles for therapy of brain diseases

G Loch-Neckel, AT Matos, AR Vaz… - Frontiers in …, 2022 - frontiersin.org
Small extracellular vesicles (sEVs) have∼ 30–200 nm diameter size and may act as carriers
of different cargoes, depending on the cell of origin or on the physiological/pathological …

Comprehensive review of nutraceuticals against cognitive decline associated with Alzheimer's disease

EE Reza-Zaldívar, DA Jacobo-Velázquez - ACS omega, 2023 - ACS Publications
Nowadays, nutraceuticals are being incorporated into functional foods or used as
supplements with nonpharmacological approaches in the prevention and management of …