Malaria: influence of Anopheles mosquito saliva on Plasmodium infection

G Arora, YM Chuang, P Sinnis, G Dimopoulos… - Trends in …, 2023 - cell.com
Malaria is caused by Plasmodium protozoa that are transmitted by anopheline mosquitoes.
Plasmodium sporozoites are released with saliva when an infected female mosquito takes a …

Host-parasite interactions during Plasmodium infection: Implications for immunotherapies

P Chandley, R Ranjan, S Kumar, S Rohatgi - Frontiers in Immunology, 2023 - frontiersin.org
Malaria is a global infectious disease that remains a leading cause of morbidity and mortality
in the developing world. Multiple environmental and host and parasite factors govern the …

A mosquito AgTRIO mRNA vaccine contributes to immunity against malaria

YM Chuang, MG Alameh, S Abouneameh, H Raduwan… - NPJ vaccines, 2023 - nature.com
Malaria begins when an infected mosquito injects saliva containing Plasmodium sporozoites
into the skin of a vertebrate host. To prevent malaria, vaccination is the most effective …

Aedes aegypti D7 long salivary proteins modulate blood feeding and parasite infection

I Martin-Martin, BB Kojin, A Aryan, AE Williams… - Mbio, 2023 - Am Soc Microbiol
Mosquito saliva facilitates blood meal acquisition through pharmacologically active
compounds that prevent host hemostasis and immune responses. Here, we generated two …

Recognition of Aedes aegypti Mosquito Saliva Protein LTRIN by the Human Receptor LTβR for Controlling the Immune Response

SN Loh, IR Anthony, E Gavor, XS Lim, RM Kini, YK Mok… - Biology, 2024 - mdpi.com
Simple Summary In this study, we present the characterization of Aedes aegypti mosquito
salivary protein, LTRIN (lymphotoxin β receptor inhibitor), a key facilitator of ZIKV …

Host skin immunity to arthropod vector bites: From mice to humans

J Lacsina, R Kissinger, J Doehl, MM Disotuar… - Frontiers in Tropical …, 2024 - frontiersin.org
Infections caused by vector-borne pathogens impose a significant burden of morbidity and
mortality in a global scale. In their quest for blood, hematophagous arthropods penetrate the …

[HTML][HTML] Two mosquito salivary antigens demonstrate promise as biomarkers of recent exposure to P. falciparum infected mosquito bites

S Lapidus, MM Goheen, M Sy, AB Deme, IM Ndiaye… - medRxiv, 2024 - ncbi.nlm.nih.gov
Background: Measuring malaria transmission intensity using the traditional entomological
inoculation rate is difficult. Antibody responses to mosquito salivary proteins such as SG6 …