Nanocrystals for controlled delivery: state of the art and approved drug products

RS Kalhapure, S Palekar, K Patel… - Expert opinion on drug …, 2022 - Taylor & Francis
Introduction Controlled/extended-release formulations offer numerous benefits over
conventional especially reduced side effects, improved therapeutic outcomes, and high …

Nanocrystal Preparation of Poorly Water-Soluble Drugs with Low Metal Contamination Using Optimized Bead-Milling Technology

H Tanaka, Y Ochii, Y Moroto, D Hirata, T Ibaraki… - Pharmaceutics, 2022 - mdpi.com
Nanocrystal preparation using bead milling is an important technology to enhance the
solubility of poorly water-soluble drugs. However, there are safety concerns regarding the …

[PDF][PDF] ビーズミルを用いたコンタミレスナノ粉砕技術の開発に関する研究

田中宏典 - kobeyakka.repo.nii.ac.jp
緒言現在, 医薬品開発においては, ハイスループットスクリーニング技術の進歩に伴い,
優れた薬理作用を有する新規医薬品候補化合物が創製されるようになった. 一方 …