COVID-19 and the promise of small molecule therapeutics: Are there lessons to be learnt?

WS Ho, R Zhang, YL Tan, CLL Chai - Pharmacological Research, 2022 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic had grounded the world to a
standstill. As the disease continues to rage two years on, it is apparent that effective …

Recommendations for safe dental care: A systematic review of clinical practice guidelines in the first year of the COVID-19 pandemic

NF Deana, A Seiffert, Y Aravena-Rivas… - International journal of …, 2021 - mdpi.com
In the context of a pandemic, the rapid development of clinical practice guidelines (CPGs) is
critical to guide dental staff towards the safe provision of dental care; detailed knowledge of …

[HTML][HTML] Utilization of complementary and alternative medicine for the prevention of COVID-19 infection in Ghana: A national cross-sectional online survey

IA Kretchy, JA Boadu, JP Kretchy, K Agyabeng… - Preventive medicine …, 2021 - Elsevier
Complementary and alternative medicine (CAM) use is widespread and has played critical
roles in preventing infections, including previous coronaviruses. This study sought to …

Aptamers for SARS‐CoV‐2: Isolation, Characterization, and Diagnostic and Therapeutic Developments

R Amini, Z Zhang, J Li, J Gu, JD Brennan… - Analysis & …, 2022 - Wiley Online Library
The SARS‐CoV‐2 virus and COVID‐19 pandemic continue to demand effective diagnostic
and therapeutic solutions. Finding these solutions requires highly functional molecular …

Approaches to the potential therapy of COVID-19: a general overview from the medicinal chemistry perspective

JC Menéndez - Molecules, 2022 - mdpi.com
In spite of advances in vaccination, control of the COVID-19 pandemic will require the use of
pharmacological treatments against SARS-CoV2. Their development needs to consider the …

A comprehensive review on the efficacy of several pharmacologic agents for the treatment of COVID-19

F Haddad, G Dokmak, R Karaman - Life, 2022 - mdpi.com
Simple Summary Treatments for coronavirus disease-2019 (COVID-19) have utilized a
variety of medications, including antivirals, immunomodulators, and other therapeutics such …

A multi-omics longitudinal study reveals alteration of the leukocyte activation pathway in COVID-19 patients

K Suvarna, A Salkar, V Palanivel… - Journal of Proteome …, 2021 - ACS Publications
Severe coronavirus disease 2019 (COVID-19) infection may lead to lung injury, multi-organ
failure, and eventually death. Cytokine storm due to excess cytokine production has been …

Bispecific repurposed medicines targeting the viral and immunological arms of COVID-19

MA Redhead, CD Owen, L Brewitz, AH Collette… - Scientific reports, 2021 - nature.com
Effective agents to treat coronavirus infection are urgently required, not only to treat COVID-
19, but to prepare for future outbreaks. Repurposed anti-virals such as remdesivir and …

How to use COVID-19 antiviral drugs in patients with chronic kidney disease

A Kale, V Shelke, N Dagar, HJ Anders… - Frontiers in …, 2023 - frontiersin.org
Antiviral drugs such as Remdesivir (Veklury), Nirmatrelvir with Ritonavir (Paxlovid),
Azvudine, and Molnupiravir (Lagevrio) can reduce the risk for severe and fatal Coronavirus …

Safety profile of COVID-19 drugs in a real clinical setting

MN Chiu, M Bhardwaj, SP Sah - European journal of clinical pharmacology, 2022 - Springer
Purpose The coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) virus has affected millions all over the world and has …