Advancing scientific discovery requires investigators to embrace research practices that
increase transparency and disclosure about materials, methods, and outcomes. Several …

Trace metals can be divided into two subgroups considering their pathophysiological effects:
the first consists of microelements essential for life (arsenic, cobalt, chromium, copper …

The newborn immune system is characterized by diminished immune responses that leave
infants vulnerable to virus-mediated disease and make vaccination more challenging …

Ischemic heart diseases remain the leading cause of death globally, and stem cell-based
therapy has been investigated as a potential approach for cardiac repair. Due to poor …

Peyer's patches (PPs) are B cell-rich sites of intestinal immune induction, yet PP-associated
B cell signaling, activation, and differentiation are poorly defined. Single-cell and spatial …

Genome editing has the potential to treat genetic diseases in a variety of tissues, including
the lung. We have previously developed and validated a dual adeno-associated virus (AAV) …

Nonhuman primates are important preclinical models for translational, reproductive, and
developmental science. Clinical evaluation of human fetal development is performed using …

The brain atlas is essential for exploring the anatomical structure and function of the brain.
Non-human primates, such as cynomolgus macaque, have received increasing attention …

Advanced technologies of targeted differentiation and genetic engineering in pluripotent
stem cells (PSCs) offer production of purposefully designed cells for transplantation. Here …

The tree shrew (Tupaia belangeri) has long been proposed as a suitable alternative to non-
human primates (NHPs) in biomedical and laboratory research due to its close evolutionary …