Comparison of beta-cell function between Hong Kong Chinese with young-onset type 2 diabetes and late-onset type 2 diabetes

Y Fan, B Fan, ESH Lau, CKP Lim, H Wu… - Diabetes research and …, 2023 - Elsevier
Aims We compared beta-cell function in Chinese with type 2 diabetes diagnosed at age< 40
years (young-onset diabetes, YOD) and≥ 40 years (late-onset diabetes, LOD). Methods In …

The use of technology in type 2 diabetes and prediabetes: a narrative review

AL Liarakos, JZM Lim, L Leelarathna, EG Wilmot - Diabetologia, 2024 - Springer
The increasing incidence of type 2 diabetes, which represents 90% of diabetes cases
globally, is a major public health concern. Improved glucose management reduces the risk …

[HTML][HTML] Chemokine CX3CL1 (Fractalkine) Signaling and Diabetic Encephalopathy

M Wątroba, AD Grabowska, D Szukiewicz - International Journal of …, 2024 - mdpi.com
Diabetes mellitus (DM) is the most common metabolic disease in humans, and its
prevalence is increasing worldwide in parallel with the obesity pandemic. A lack of insulin or …

Identifying subtypes of type 2 diabetes mellitus with machine learning: development, internal validation, prognostic validation and medication burden in linked …

MA Mizani, A Dashtban, L Pasea, Q Zeng… - BMJ Open Diabetes …, 2024 - drc.bmj.com
Introduction None of the studies of type 2 diabetes (T2D) subtyping to date have used linked
population-level data for incident and prevalent T2D, incorporating a diverse set of …

Early-Onset Type 2 Diabetes and Tirzepatide Treatment: A Post Hoc Analysis From the SURPASS Clinical Trial Program

P Zeitler, RJ Galindo, MJ Davies, BK Bergman… - Diabetes …, 2024 - Am Diabetes Assoc
OBJECTIVE We evaluated baseline characteristics of participants with early-onset type 2
diabetes (T2D) from the SURPASS program and tirzepatide's effects on glycemic control …

Adherence to a Mediterranean diet is associated with a lower risk of diabetic kidney disease among individuals with hyperglycemia: a prospective cohort study

C Qu, J Zhao, J Lai, X Wu, P Huang, T Zhu, Y Li, T Liu… - BMC medicine, 2024 - Springer
Background Type 2 diabetes is associated with a variety of complications, including micro-
and macrovascular complications, neurological manifestations and poor wound healing …

Insulin secretion defect in children and adolescents with obesity: clinical and molecular genetic characterization

H Enders-Seidlitz, K Raile, M Gong… - Journal of Diabetes …, 2024 - Wiley Online Library
Introduction. Childhood obesity is increasing worldwide and presents as a global health
issue due to multiple metabolic comorbidities. About 1% of adolescents with obesity develop …

[HTML][HTML] Amphiphilic, lauric acid-coupled pluronic-based nano-micellar system for efficient glipizide delivery

V Kumar, N Poonia, P Kumar, PK Verma… - Saudi Pharmaceutical …, 2024 - Elsevier
Glipizide; an insulin secretagogue belonging to the sulfonylurea class, is a widely used
antidiabetic drug for managing type 2 diabetes. However, the need for life-long …

Maackiain Mimics Caloric Restriction through aak-2-Mediated Lipid Reduction in Caenorhabditis elegans

SG Mladenova, MN Todorova, MS Savova… - International Journal of …, 2023 - mdpi.com
Obesity prevalence is becoming a serious global health and economic issue and is a major
risk factor for concomitant diseases that worsen the quality and duration of life. Therefore …

Precision Medicine to Redefine Insulin Secretion and Monogenic Diabetes-Randomized Controlled Trial (PRISM-RCT) in Chinese patients with young-onset diabetes …

YN Fan, B Fan, C Lim, ESH Lau, STF Tsoi… - BMJ Open Diabetes …, 2024 - drc.bmj.com
Introduction We designed and implemented a patient-centered, data-driven, holistic care
model with evaluation of its impacts on clinical outcomes in patients with young-onset type 2 …