Cardiac Injury Biomarkers and the Risk of Death in Patients with COVID‐19: A Systematic Review and Meta‐Analysis

SH Alzahrani, MW Al-Rabia - Cardiology research and practice, 2021 - Wiley Online Library
Background. Cardiac complications may develop in a proportion of patients with the novel
coronavirus disease (COVID‐19), which may influence their prognosis. Objectives. To …

A novel penalized inverse‐variance weighted estimator for Mendelian randomization with applications to COVID‐19 outcomes

S Xu, P Wang, WK Fung, Z Liu - Biometrics, 2023 - Wiley Online Library
Mendelian randomization utilizes genetic variants as instrumental variables (IVs) to estimate
the causal effect of an exposure variable on an outcome of interest even in the presence of …

Upregulation of cAMP prevents antibody-mediated thrombus formation in COVID-19

J Zlamal, K Althaus, H Jaffal, H Häberle, L Pelzl… - Blood …, 2022 - ashpublications.org
Thromboembolic events are frequently reported in patients infected with the SARS-CoV-2
virus. The exact mechanisms of COVID-19-associated hypercoagulopathy, however, remain …

Baseline Plasma Gas6 Protein Elevation Predicts Adverse Outcomes in Hospitalized COVID‐19 Patients

S Tonello, M Rizzi, E Matino, M Costanzo… - Disease …, 2022 - Wiley Online Library
Reliable biomarkers allowing early patients' stratification for the risk of adverse outcomes in
COVID‐19 are lacking. Gas6, together with its tyrosine kinase receptors named TAM, is …

Erythrocytes induce vascular dysfunction in COVID-19

A Mahdi, A Collado, J Tengbom, T Jiao… - Basic to Translational …, 2022 - jacc.org
Current knowledge regarding mechanisms underlying cardiovascular complications in
patients with COVID-19 is limited and urgently needed. We shed light on a previously …

Coagulopathy of dengue and COVID-19: clinical considerations

A Islam, C Cockcroft, S Elshazly, J Ahmed… - Tropical Medicine and …, 2022 - mdpi.com
Thrombocytopenia and platelet dysfunction commonly occur in both dengue and COVID-19
and are related to clinical outcomes. Coagulation and fibrinolytic pathways are activated …

Protective efficacy of novel engineered human Ace2-FC fusion protein against Pan-SARS-Cov-2 infection in vitro and in vivo

B Yu, A Drelich, J Hsu, V Tat, BH Peng… - Journal of medicinal …, 2023 - ACS Publications
Enduring occurrence of severe COVID-19 for unvaccinated, aged, or immunocompromised
individuals remains an urgent need. Soluble human angiotensin-converting enzyme 2 …

The effects of vitamin C on the multiple pathophysiological stages of COVID-19

JR Miranda-Massari, AP Toro, D Loh, JR Rodriguez… - Life, 2021 - mdpi.com
Currently available anti-viral drugs may be useful in reducing the viral load but are not
providing the necessary physiological effects to reduce the SARS-CoV-2 complications …

Renin–angiotensin system blockade in the COVID-19 pandemic

JB Cohen, AM South, HA Shaltout… - Clinical Kidney …, 2021 - academic.oup.com
In the early months of the coronavirus disease 2019 (COVID-19) pandemic, a hypothesis
emerged suggesting that pharmacologic inhibitors of the renin–angiotensin system (RAS) …

Protein posttranslational signatures identified in COVID-19 patient plasma

P Vedula, HY Tang, DW Speicher, A Kashina… - Frontiers in Cell and …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a highly contagious
virus of the coronavirus family that causes coronavirus disease-19 (COVID-19) in humans …