[HTML][HTML] Cell fusion as a link between the SARS-CoV-2 spike protein, COVID-19 complications, and vaccine side effects

Y Lazebnik - Oncotarget, 2021 - ncbi.nlm.nih.gov
A distinctive feature of the SARS-CoV-2 spike protein is its ability to efficiently fuse cells, thus
producing syncytia found in COVID-19 patients. This commentary proposes how this ability …

COVID-19 and immunothrombosis: Pathophysiology and therapeutic implications

MS Lim, S Mcrae - Critical Reviews in Oncology/Hematology, 2021 - Elsevier
The coagulopathy of COVID-19 is characterised by significantly elevated D Dimer and
fibrinogen, mild thrombocytopenia and a mildly prolonged PT/APTT. A high incidence of …

COVID-19 and pulmonary embolism outcomes among hospitalized patients in the united states: a propensity-matched analysis of national inpatient sample

A Nasrullah, K Gangu, NB Shumway, HR Cannon… - Vaccines, 2022 - mdpi.com
Venous thromboembolism, in particular, pulmonary embolism (PE), is a significant
contributor to the morbidity and mortality associated with COVID-19. In this study, we utilized …

Cardiovascular and cerebrovascular complications with COVID-19

A Greenberg, G Pemmasani, S Yandrapalli… - Cardiology in …, 2021 - journals.lww.com
Abstract The coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory
syndrome coronavirus-2 has affected the health of people across the globe. Cardiovascular …

COVID-19 biomarkers at the crossroad between patient stratification and targeted therapy: the role of validated and proposed parameters

M Rizzi, D D'Onghia, S Tonello, R Minisini… - International Journal of …, 2023 - mdpi.com
Clinical knowledge about SARS-CoV-2 infection mechanisms and COVID-19
pathophysiology have enormously increased during the pandemic. Nevertheless, because …

Role of serum E-selectin as a biomarker of infection severity in coronavirus disease 2019

A Oliva, E Rando, D Al Ismail, M De Angelis… - Journal of Clinical …, 2021 - mdpi.com
Introduction: E-selectin is a recognized marker of endothelial activation; however, its place in
Coronavirus Disease 2019 (COVID-19) has not been fully explored. Aims of the study are to …

[HTML][HTML] Endothelial inflammation and dysfunction in COVID-19

Y Sbirkov, V Dzharov, K Todorova, S Hayrabedyan… - Vasa, 2022 - econtent.hogrefe.com
The biggest challenge in the COVID-19 pandemic besides the spread of the SARS-CoV-2
virus is to reduce mortality rates. As the number of cases continues to rise and new variants …

The role of von Willebrand factor in the pathogenesis of pulmonary vascular thrombosis in COVID-19

AS Babkina, IV Ostrova, MY Yadgarov, AN Kuzovlev… - Viruses, 2022 - mdpi.com
The increased plasma levels of von Willebrand factor (VWF) in patients with COVID-19 was
reported in many studies, and its correlation with disease severity and mortality suggest its …

Targeting the complement cascade in the pathophysiology of COVID-19 disease

N Ng, CA Powell - Journal of Clinical Medicine, 2021 - mdpi.com
Severe coronavirus disease 2019 causes multi-organ dysfunction with significant morbidity
and mortality. Mounting evidence implicates maladaptive over-activation of innate immune …

ABO rs657152 and Blood Groups Are as Predictor Factors of COVID‐19 Mortality in the Iranian Population

F Mirzaei Gheinari, F Sakhaee, M Gholami… - Disease …, 2022 - Wiley Online Library
Several studies have discovered a relationship between specific blood types, genetic
variations of the ABO gene, and coronavirus disease 2019 (COVID‐19). Therefore, the aim …