COVID-19: characteristics and therapeutics

R Chilamakuri, S Agarwal - Cells, 2021 - mdpi.com
Novel coronavirus (COVID-19 or 2019-nCoV or SARS-CoV-2), which suddenly emerged in
December 2019 is still haunting the entire human race and has affected not only the …

A critical review on environmental presence of pharmaceutical drugs tested for the covid-19 treatment

RP Nippes, PD Macruz, GN da Silva… - Process Safety and …, 2021 - Elsevier
Abstract On March 11, 2020, the World Health Organization (WHO) declared COVID-19 a
pandemic. The outbreak caused a worldwide impact, becoming a health threat to the …

Inflammatory mechanisms in COVID-19 and atherosclerosis: current pharmaceutical perspectives

M Sagris, P Theofilis, AS Antonopoulos… - International journal of …, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has been associated with excess mortality worldwide. The …

Computational identification of host genomic biomarkers highlighting their functions, pathways and regulators that influence SARS-CoV-2 infections and drug …

MP Mosharaf, MS Reza, MK Kibria, FF Ahmed… - Scientific reports, 2022 - nature.com
The pandemic threat of COVID-19 has severely destroyed human life as well as the
economy around the world. Although, the vaccination has reduced the outspread, but …

[HTML][HTML] Prevention and treatment of COVID-19: Focus on interferons, chloroquine/hydroxychloroquine, azithromycin, and vaccine

BM Bakadia, F He, T Souho, L Lamboni… - Biomedicine & …, 2021 - Elsevier
The ongoing pandemic caused by the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has drawn the attention of researchers and clinicians from several disciplines …

Therapeutic effectiveness and safety of repurposing drugs for the treatment of COVID-19: position standing in 2021

S Alam, TB Kamal, MMR Sarker, JR Zhou… - Frontiers in …, 2021 - frontiersin.org
COVID-19, transmitted by SARS-CoV-2, is one of the most serious pandemic situations in
the history of mankind, and has already infected a huge population across the globe. This …

Role of SARS-CoV-2-induced cytokine storm in multi-organ failure: Molecular pathways and potential therapeutic options

Y Nazerian, M Ghasemi, Y Yassaghi, A Nazerian… - International …, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) outbreak has become a global public health
emergency and has led to devastating results. Mounting evidence proposes that the disease …

[HTML][HTML] Analysis of neurological adverse events reported in VigiBase from COVID-19 vaccines

S Dutta, R Kaur, J Charan, P Bhardwaj, SR Ambwani… - Cureus, 2022 - ncbi.nlm.nih.gov
Background: Fifteen COVID-19 vaccines have been granted emergency approval before the
completion of conventional phases of clinical trials. The present study aimed to analyze the …

Pharmacogenomics and COVID-19: clinical implications of human genome interactions with repurposed drugs

OA Badary - The pharmacogenomics journal, 2021 - nature.com
The outbreak of Coronavirus disease 2019 (COVID-19) has evolved into an emergent global
pandemic. Many drugs without established efficacy are being used to treat COVID-19 …

Baricitinib combination therapy: a narrative review of repurposed Janus kinase inhibitor against severe SARS-CoV-2 infection

M Akbarzadeh-Khiavi, M Torabi, L Rahbarnia, A Safary - Infection, 2022 - Springer
Abstract Purpose The Coronavirus disease 2019 (COVID-19) pandemic is one of the most
devastating global problems. Regarding the lack of disease-specific treatments, repurposing …