Molecular mechanisms of vascular health: insights from vascular aging and calcification
Cardiovascular disease is the most common cause of death worldwide, especially beyond
the age of 65 years, with the vast majority of morbidity and mortality due to myocardial …
the age of 65 years, with the vast majority of morbidity and mortality due to myocardial …
[HTML][HTML] Timing of lifespan influences on brain and cognition
Modifiable risk and protective factors for boosting brain and cognitive development and
preventing neurodegeneration and cognitive decline are embraced in neuroimaging …
preventing neurodegeneration and cognitive decline are embraced in neuroimaging …
[HTML][HTML] A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease
Identification of individuals at highest risk of coronary artery disease (CAD)—ideally before
onset—remains an important public health need. Prior studies have developed genome …
onset—remains an important public health need. Prior studies have developed genome …
Coronary artery calcium score and polygenic risk score for the prediction of coronary heart disease events
Importance Coronary artery calcium score and polygenic risk score have each separately
been proposed as novel markers to identify risk of coronary heart disease (CHD), but no …
been proposed as novel markers to identify risk of coronary heart disease (CHD), but no …
[PDF][PDF] 2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of …
M Brunström, M Burnier, G Grassi… - J …, 2023 - docred-strapi-cms-prod.s3.sa-east-1 …
Document Reviewers: Luis Alcocer (Mexico), Christina Antza (Greece), Mustafa Arici
(Turkey), Eduardo Barbosa (Brazil), Adel Berbari (Lebanon), Luıs Bronze (Portugal), John …
(Turkey), Eduardo Barbosa (Brazil), Adel Berbari (Lebanon), Luıs Bronze (Portugal), John …
Precision medicine in complex diseases—Molecular subgrouping for improved prediction and treatment stratification
Complex diseases are caused by a combination of genetic, lifestyle, and environmental
factors and comprise common noncommunicable diseases, including allergies …
factors and comprise common noncommunicable diseases, including allergies …
Polygenic risk scores for the prediction of cardiometabolic disease
Cardiometabolic diseases contribute more to global morbidity and mortality than any other
group of disorders. Polygenic risk scores (PRSs), the weighted summation of individually …
group of disorders. Polygenic risk scores (PRSs), the weighted summation of individually …
[HTML][HTML] Frequent questions and responses on the 2022 lipoprotein (a) consensus statement of the European Atherosclerosis Society
F Kronenberg, S Mora, ESG Stroes, BA Ference… - Atherosclerosis, 2023 - Elsevier
Abstract In 2022, the European Atherosclerosis Society (EAS) published a new consensus
statement on lipoprotein (a)[Lp (a)], summarizing current knowledge about its causal …
statement on lipoprotein (a)[Lp (a)], summarizing current knowledge about its causal …
Current state and future of polygenic risk scores in cardiometabolic disease: a scoping review
A polygenic risk score (PRS) is derived from a genome-wide association study and
represents an aggregate of thousands of single-nucleotide polymorphisms that provide a …
represents an aggregate of thousands of single-nucleotide polymorphisms that provide a …
Wrestling with social and behavioral genomics: risks, potential benefits, and ethical responsibility
In this consensus report by a diverse group of academics who conduct and/or are concerned
about social and behavioral genomics (SBG) research, the authors recount the often‐ugly …
about social and behavioral genomics (SBG) research, the authors recount the often‐ugly …