The global burden of neurological disorders: translating evidence into policy

VL Feigin, T Vos, E Nichols, MO Owolabi… - The Lancet …, 2020 - thelancet.com
Neurological disorders are the leading cause of disability and the second leading cause of
death worldwide. In the past 30 years, the absolute numbers of deaths and people with …

Free radical damage in ischemia‐reperfusion injury: an obstacle in acute ischemic stroke after revascularization therapy

MS Sun, H Jin, X Sun, S Huang… - Oxidative medicine …, 2018 - Wiley Online Library
Acute ischemic stroke is a common cause of morbidity and mortality worldwide.
Thrombolysis with recombinant tissue plasminogen activator and endovascular …

[HTML][HTML] Post-stroke cognitive impairment: epidemiology, mechanisms and management

JH Sun, L Tan, JT Yu - Annals of translational medicine, 2014 - ncbi.nlm.nih.gov
Post-stroke cognitive impairment occurs frequently in the patients with stroke. The
prevalence of post-stroke cognitive impairment ranges from 20% to 80%, which varies for …

Factors influencing the decline in stroke mortality: a statement from the American Heart Association/American Stroke Association

DT Lackland, EJ Roccella, AF Deutsch, M Fornage… - Stroke, 2014 - Am Heart Assoc
Background and Purpose—Stroke mortality has been declining since the early 20th century.
The reasons for this are not completely understood, although the decline is welcome. As a …

Neurogenesis and inflammation after ischemic stroke: what is known and where we go from here

MK Tobin, JA Bonds, RD Minshall… - Journal of Cerebral …, 2014 - journals.sagepub.com
This review covers the pathogenesis of ischemic stroke and future directions regarding
therapeutic options after injury. Ischemic stroke is a devastating disease process affecting …

Microglial responses after ischemic stroke and intracerebral hemorrhage

RA Taylor, LH Sansing - Journal of Immunology Research, 2013 - Wiley Online Library
Stroke is a leading cause of death worldwide. Ischemic stroke is caused by blockage of
blood vessels in the brain leading to tissue death, while intracerebral hemorrhage (ICH) …

Revisiting cerebral postischemic reperfusion injury: new insights in understanding reperfusion failure, hemorrhage, and edema

J Bai, PD Lyden - International Journal of Stroke, 2015 - journals.sagepub.com
Cerebral postischemic reperfusion injury is defined as deterioration of ischemic brain tissue
that parallels and antagonizes the benefits of restoring cerebral circulation after therapeutic …

Mmp-9 inhibition: a therapeutic strategy in ischemic stroke

M Chaturvedi, L Kaczmarek - Molecular neurobiology, 2014 - Springer
Ischemic stroke is a leading cause of disability worldwide. In cerebral ischemia there is an
enhanced expression of matrix metallo-proteinase-9 (MMP-9), which has been associated …

Factors affecting post-stroke motor recovery: implications on neurotherapy after brain injury

A Alawieh, J Zhao, W Feng - Behavioural brain research, 2018 - Elsevier
Neurological disorders are a major cause of chronic disability globally among which stroke
is a leading cause of chronic disability. The advances in the medical management of stroke …

Trends in acute ischemic stroke hospitalizations in the United States

L Ramirez, MA Kim‐Tenser, N Sanossian… - Journal of the …, 2016 - Am Heart Assoc
Background Population‐based studies have revealed declining acute ischemic stroke (AIS)
hospitalization rates in the United States, but no study has assessed recent temporal trends …