In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …

This review focuses on the neuronal and circuit mechanisms involved in the generation of
the theta (θ) rhythm and of its participation in behavior. Data have accumulated indicating …

Oestrogen depletion in rodents and humans leads to inactivity, fat accumulation and
diabetes,, underscoring the conserved metabolic benefits of oestrogen that inevitably …

Social interactions are essential for mammalian life and are regulated by evolutionary
conserved neuronal mechanisms. An individual's internal state, experiences, and the nature …

Locomotion is a universal behaviour that provides animals with the ability to move between
places. Classical experiments have used electrical microstimulation to identify brain regions …

Interneurons expressing cholecystokinin (CCK) and parvalbumin (PV) constitute two key
GABAergic controllers of hippocampal pyramidal cell output. Although the temporally …

Diverse computations in the neocortex are aided by specialized GABAergic interneurons
(INs), which selectively target other INs. However, much less is known about how these …

Neural networks display the ability to transform forward-ordered activity patterns into reverse-
ordered, retrospective sequences. The mechanisms underlying this transformation remain …

Animals can navigate vast distances and often display behaviours or activities that indicate a
detailed, internal spatial representation of their surrounding environment or a 'cognitive …

The medial prefrontal cortex (mPFC) integrates information from cortical and sub-cortical
areas and contributes to the planning and initiation of behaviour. A potential mechanism for …