A class of near-infrared fluorescence (NIRF) heptamethine cyanine dyes that are taken up
and accumulated specifically in cancer cells without chemical conjugation have recently …

Mercury exists in the environment in various forms, all of which pose a risk to human health.
Despite guidelines regulating the industrial release of mercury into the environment …

In recent years, cancer phototherapy has been extensively studied as noninvasive cancer
treatment. To present efficient recognition toward cancer cells, most photosensitizers (PSs) …

One approach to experimental science involves creating hypotheses, then testing them by
varying one or more independent variables, and assessing the effects of this variation on the …

Many new chemical entities are discovered with high therapeutic potential, however, many
of these compounds exhibit unfavorable pharmacokinetic properties due to poor solubility …

Although oral drug administration is currently the favorable route of administration, intestinal
drug absorption is challenged by several highly variable and poorly predictable processes …

Protein expression levels of drug-metabolizing enzymes and transporters in human jejunal
tissues excised from morbidly obese subjects during gastric bypass surgery were evaluated …

Near-infrared (NIR) fluorescence imaging agents are promising tools for noninvasive cancer
imaging. This study explored the specific uptake and retention of a NIR heptamethine …

The organic anion–transporting polypeptide (OATP) 2B1 which is ubiquitously expressed in
the human body is assumed to play an important role in the cellular uptake of many drugs …

Organic anion transporting polypeptide 2B1 (OATP2B1) is a widely expressed membrane
transporter with diverse substrate specificity. In vitro and clinical studies suggest a role for …