Structure–Activity Relationship Studies of Chalcones and Diarylpentanoids with Antitumor Activity: Potency and Selectivity Optimization
J Moreira, JB Loureiro, D Correia, A Palmeira… - Pharmaceuticals, 2023 - mdpi.com
We previously reported that chalcone CM-M345 (1) and diarylpentanoid BP-C4 (2) induced
p53-dependent growth inhibitory activity in human cancer cells. Herein, CM-M345 (1) and …
p53-dependent growth inhibitory activity in human cancer cells. Herein, CM-M345 (1) and …
Synthesis of Symmetrical Monocarbonyl Analogs of Curcumin Containing a 2-Bromobenzylidene Moiety and Spectrophotometric Assessment of Their Reactivity with 2 …
Z Lozanovski, I Todorovska, K Dragarska… - Chemistry …, 2023 - mdpi.com
The cross-conjugated dienones containing the 1, 5-diaryl-3-oxo-1, 4-pentadienyl
pharmacophore have diverse biological activities. These sometimes-called monocarbonyl …
pharmacophore have diverse biological activities. These sometimes-called monocarbonyl …
Discovery of a New Chalcone-Trimethoxycinnamide Hybrid with Antimitotic Effect: Design, Synthesis, and Structure—Activity Relationship Studies
J Moreira, PMA Silva, M Barros, L Saraiva, M Pinto… - Pharmaceuticals, 2023 - mdpi.com
In this work, the design and synthesis of a new chalcone-trimethoxycinnamide hybrid (7)
based on the combination of subunits of two promising antiproliferative compounds (CM …
based on the combination of subunits of two promising antiproliferative compounds (CM …
[PDF][PDF] Synthesis of Symmetrical Monocarbonyl Analogs of Curcumin (MACs) Containing 2-Bromobenzylidene Moiety and Spectrophotometric Assessment of Their …
Z Lozanovski, I Todorovska, K Dragarska, J Bogdanov - 2023 - sciforum.net
The cross-conjugated dienones containing the 1, 5-diaryl-3-oxo-1, 4-pentadienyl
pharmacophore have diverse biological activities. These sometimes called monocarbonyl …
pharmacophore have diverse biological activities. These sometimes called monocarbonyl …