Perioperative opioid analgesia—when is enough too much? A review of opioid-induced tolerance and hyperalgesia

LA Colvin, F Bull, TG Hales - The Lancet, 2019 - thelancet.com
Opioids are a mainstay of acute pain management but can have many adverse effects,
contributing to problematic long-term use. Opioid tolerance (increased dose needed for …

Postoperative pain management in the era of ERAS: an overview

GP Joshi, H Kehlet - Best Practice & Research Clinical Anaesthesiology, 2019 - Elsevier
Enhanced recovery after surgery (ERAS) programmes are increasingly becoming standard
of care for several surgical procedures. However, compliance with ERAS protocols including …

[HTML][HTML] CDC clinical practice guideline for prescribing opioids for pain—United States, 2022

D Dowell - MMWR. Recommendations and reports, 2022 - cdc.gov
This guideline provides recommendations for clinicians providing pain care, including those
prescribing opioids, for outpatients aged≥ 18 years. It updates the CDC Guideline for …

Opioid versus opioid-free analgesia after surgical discharge: a systematic review and meta-analysis of randomised trials

JF Fiore, C El-Kefraoui, MA Chay, P Nguyen-Powanda… - The Lancet, 2022 - thelancet.com
Background Excessive opioid prescribing after surgery has contributed to the current opioid
crisis; however, the value of prescribing opioids at surgical discharge remains uncertain. We …

Perioperative pain management and opioid stewardship: a practical guide

SJ Hyland, KK Brockhaus, WR Vincent, NZ Spence… - Healthcare, 2021 - mdpi.com
Surgical procedures are key drivers of pain development and opioid utilization globally.
Various organizations have generated guidance on postoperative pain management …

An international multidisciplinary consensus statement on the prevention of opioid‐related harm in adult surgical patients

N Levy, J Quinlan, K El‐Boghdadly, WJ Fawcett… - …, 2021 - Wiley Online Library
This international multidisciplinary consensus statement was developed to provide balanced
guidance on the safe peri‐operative use of opioids in adults. An international panel of …

Current issues in the use of opioids for the management of postoperative pain: a review

PE Macintyre, J Quinlan, N Levy, DN Lobo - JAMA surgery, 2022 - jamanetwork.com
Importance Uncontrolled and indiscriminate prescribing of opioids has led to an opioid crisis
that started in North America and spread throughout high-income countries. The aim of this …

Persistent postoperative opioid use: a systematic literature search of definitions and population-based cohort study

NK Jivraj, F Raghavji, J Bethell, DN Wijeysundera… - …, 2020 - pubs.asahq.org
Background While persistent opioid use after surgery has been the subject of a large
number of studies, it is unknown how much variability in the definition of persistent use …

The effect of ultrasound-guided erector spinae plane block on postsurgical pain: a meta-analysis of randomized controlled trials

MC Kendall, L Alves, LL Traill, GS De Oliveira - BMC anesthesiology, 2020 - Springer
Background The effect of erector spinae plane block has been evaluated by clinical trials
leading to a diversity of results. The main objective of the current investigation is to compare …

[HTML][HTML] Reduced postoperative pain using nociception level-guided fentanyl dosing during sevoflurane anaesthesia: a randomised controlled trial

F Meijer, M Honing, T Roor, S Toet, P Calis… - British Journal of …, 2020 - Elsevier
Background The majority of postoperative patients report moderate to severe pain, possibly
related to opioid underdosing or overdosing during surgery. Objective guidance of opioid …