[HTML][HTML] The biological and clinical significance of emerging SARS-CoV-2 variants

K Tao, PL Tzou, J Nouhin, RK Gupta… - Nature Reviews …, 2021 - nature.com
The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …

[HTML][HTML] SARS-CoV-2 variants, vaccines, and host immunity

P Mistry, F Barmania, J Mellet, K Peta… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new beta coronavirus
that emerged at the end of 2019 in the Hubei province of China. SARS-CoV-2 causes …

[HTML][HTML] SARS-CoV-2 variants, spike mutations and immune escape

WT Harvey, AM Carabelli, B Jackson… - Nature Reviews …, 2021 - nature.com
Although most mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) genome are expected to be either deleterious and swiftly purged or relatively …

[HTML][HTML] Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity

WF Garcia-Beltran, EC Lam, KS Denis, AD Nitido… - Cell, 2021 - cell.com
Vaccination elicits immune responses capable of potently neutralizing SARS-CoV-2.
However, ongoing surveillance has revealed the emergence of variants harboring mutations …

[HTML][HTML] Antibody resistance of SARS-CoV-2 variants B. 1.351 and B. 1.1. 7

P Wang, MS Nair, L Liu, S Iketani, Y Luo, Y Guo… - Nature, 2021 - nature.com
The COVID-19 pandemic has had widespread effects across the globe, and its causative
agent, SARS-CoV-2, continues to spread. Effective interventions need to be developed to …

[HTML][HTML] Sensitivity of infectious SARS-CoV-2 B. 1.1. 7 and B. 1.351 variants to neutralizing antibodies

D Planas, T Bruel, L Grzelak, F Guivel-Benhassine… - Nature medicine, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B. 1.1. 7 and B. 1.351
variants were first identified in the United Kingdom and South Africa, respectively, and have …

[PDF][PDF] Increased resistance of SARS-CoV-2 variant P. 1 to antibody neutralization

P Wang, RG Casner, MS Nair, M Wang, J Yu… - Cell host & …, 2021 - cell.com
The emergence of SARS-CoV-2 variants has raised concerns about altered sensitivity to
antibody-mediated immunity. The relative resistance of SARS-CoV-2 variants B. 1.1. 7 and …

[PDF][PDF] LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants

K Westendorf, S Žentelis, L Wang, D Foster… - Cell reports, 2022 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal
antibodies (mAbs) can reduce the risk of hospitalization from coronavirus disease 2019 …

[HTML][HTML] In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains

RE Chen, ES Winkler, JB Case, ID Aziati, TL Bricker… - Nature, 2021 - nature.com
Rapidly emerging SARS-CoV-2 variants jeopardize antibody-based countermeasures.
Although cell culture experiments have demonstrated a loss of potency of several anti-spike …

[HTML][HTML] SARS-CoV-2 vaccines based on the spike glycoprotein and implications of new viral variants

D Martínez-Flores, J Zepeda-Cervantes… - Frontiers in …, 2021 - frontiersin.org
Coronavirus 19 Disease (COVID-19) originating in the province of Wuhan, China in 2019, is
caused by the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), whose …