Molecular mechanisms in MASLD/MASH related HCC
Liver cancer is the third leading cause of cancer-related deaths and ranks as the sixth most
prevalent cancer type globally. Nonalcoholic fatty liver disease (NAFLD) or metabolic …
prevalent cancer type globally. Nonalcoholic fatty liver disease (NAFLD) or metabolic …
[HTML][HTML] Epigenetic regulation in lean nonalcoholic fatty liver disease
I Aggeletopoulou, M Kalafateli, EP Tsounis… - International Journal of …, 2023 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD), the most prominent cause of chronic liver disease
worldwide, is a rapidly growing epidemic. It consists of a wide range of liver diseases, from …
worldwide, is a rapidly growing epidemic. It consists of a wide range of liver diseases, from …
Methylation status of LDLR, PCSK9 and LDLRAP1 is associated with cardiovascular events in familial hypercholesterolemia
E Silva Rodrigues Marçal, JB Borges, GM Bastos… - …, 2024 - Taylor & Francis
Aim: Methylation of LDLR, PCSK9 and LDLRAP1 CpG sites was assessed in patients with
familial hypercholesterolemia (FH). Methods: DNA methylation of was analyzed by …
familial hypercholesterolemia (FH). Methods: DNA methylation of was analyzed by …
Crosstalk between Epigenetics and Metabolic Reprogramming in Metabolic Dysfunction-Associated Steatotic Liver Disease-Induced Hepatocellular Carcinoma: A …
A Li, R Wang, Y Zhao, P Zhao, J Yang - Metabolites, 2024 - mdpi.com
Epigenetic and metabolic reprogramming alterations are two important features of tumors,
and their reversible, spatial, and temporal regulation is a distinctive hallmark of …
and their reversible, spatial, and temporal regulation is a distinctive hallmark of …
[HTML][HTML] Long-term outcomes following hepatectomy in patients with lean non-alcoholic fatty liver disease-associated hepatocellular carcinoma versus overweight and …
W Zhang, MY Li, ZQ Li, YK Diao, XK Liu, HW Guo… - Asian Journal of …, 2024 - Elsevier
Background & aims With the rising prevalence of non-alcoholic fatty liver disease (NAFLD)
as a significant etiology for hepatocellular carcinoma (HCC), lean NAFLD-HCC has …
as a significant etiology for hepatocellular carcinoma (HCC), lean NAFLD-HCC has …
[HTML][HTML] Global Trends of Lipid Metabolism Research in Epigenetics Field: A Bibliometric Analysis from 2012–2021
H Liu, Y Huang, S Lu, D Yuan, J Liu - International Journal of …, 2023 - mdpi.com
Most common diseases are characterized by metabolic changes, among which lipid
metabolism is a hotspot. Numerous studies have demonstrated a strong correlation between …
metabolism is a hotspot. Numerous studies have demonstrated a strong correlation between …
[HTML][HTML] RBPJ Deficiency Sensitizes Pancreatic Acinar Cells to KRAS-Mediated Pancreatic Intraepithelial Neoplasia Initiation
L Pan, MA Mulaw, J Gout, M Guo, H Zarrin… - Cellular and Molecular …, 2023 - Elsevier
Background and Aims Development of pancreatic ductal adenocarcinoma (PDAC) is a
multistep process intensively studied; however, precocious diagnosis and effective therapy …
multistep process intensively studied; however, precocious diagnosis and effective therapy …
[HTML][HTML] Identification of a six-gene signature to predict survival and immunotherapy effectiveness of gastric cancer
Q Wang, B Zhang, H Wang, M Hu, H Feng… - Frontiers in …, 2023 - frontiersin.org
Background Gastric cancer (GC) ranks as the fifth most prevalent malignancy and the
second leading cause of oncologic mortality globally. Despite staging guidelines and …
second leading cause of oncologic mortality globally. Despite staging guidelines and …