Hemocompatibility challenge of membrane oxygenator for artificial lung technology

BPN Thi, BTD Nguyen, IS Jeong, JF Kim - Acta Biomaterialia, 2022 - Elsevier
The artificial lung (AL) technology is one of the membrane-based artificial organs that partly
augments lung functions, ie blood oxygenation and CO 2 removal. It is generally employed …

Design of artificial vascular devices: Hemodynamic evaluation of shear-induced thrombogenicity

T Feaugas, G Newman, ST Calzuola… - Frontiers in …, 2023 - frontiersin.org
Blood-circulating devices such as oxygenators have offered life-saving opportunities for
advanced cardiovascular and pulmonary failures. However, such systems are limited in the …

Unprecedented strength polysiloxane-based polyurethane for 3D printing and shape memory

W Wang, S Sun, S Hu, B Yang, S He… - … Applied Materials & …, 2022 - ACS Publications
Thermoplastic polysiloxane-based polyurethane (Si-TPU) has been attracting a great deal of
attention because of the dual advantages of polysiloxane and polyurethane. However, the …

Risks and benefits of ultra–lung-protective invasive mechanical ventilation strategies with a focus on extracorporeal support

D Abrams, C Agerstrand, JR Beitler… - American journal of …, 2022 - atsjournals.org
Lung-protective ventilation strategies are the current standard of care for patients with acute
respiratory distress syndrome in an effort to provide adequate ventilatory requirements while …

[HTML][HTML] Discrete responses of erythrocytes, platelets, and von Willebrand factor to shear

CHH Chan, MJ Simmonds, KH Fraser, K Igarashi… - Journal of …, 2022 - Elsevier
Despite decades of technological advancements in blood-contacting medical devices,
complications related to shear flow-induced blood trauma are still frequently observed in …

Development and validation of a mathematical model for evaluating shear-induced damage of von Willebrand factor

Y Li, Y Xi, H Wang, A Sun, L Wang, X Deng… - Computers in Biology …, 2023 - Elsevier
Purpose To develop a mathematical model for predicting shear-induced von Willebrand
factor (vWF) function modification which can be used to guide ventricular assist devices …

A mathematical model for assessing shear induced bleeding risk

Y Li, H Wang, Y Xi, A Sun, L Wang, X Deng… - Computer Methods and …, 2023 - Elsevier
Purpose The objective of this study is to develop a bleeding risk model for assessing device-
induced bleeding risk in patients supported with blood contact medical devices (BCMDs) …

An accelerated thrombosis model for computational fluid dynamics simulations in rotary blood pumps

C Blum, S Groß-Hardt, U Steinseifer… - Cardiovascular …, 2022 - Springer
Purpose Thrombosis ranks among the major complications in blood-carrying medical
devices and a better understanding to influence the design related contribution to …

Numerical assessment of hemodynamic perspectives of a left ventricular assist device and subsequent proposal for improvisation

PK Ray, AK Das, PK Das - Computers in Biology and Medicine, 2022 - Elsevier
Due to the unavailability of donors, the use of left ventricular assist devices has emerged to
be a reliable line of alternative treatment for heart failure. However, ventricular assist devices …

[HTML][HTML] Backflow at the inlet of centrifugal blood pumps enhanced by geometrical features

F Rorro, F Fiusco, LM Broman, L Prahl Wittberg - Physics of Fluids, 2024 - pubs.aip.org
Extracorporeal life support (ECLS) includes life-saving support in severe acute cardiac
and/or pulmonary failure. In the past 20 years, centrifugal pumps have become the primary …