All endocrine glands are susceptible to neoplastic growth, yet the health consequences of
these neoplasms differ between endocrine tissues. Pituitary neoplasms are highly prevalent …

Importance Pituitary adenomas are neoplasms of the pituitary adenohypophyseal cell
lineage and include functioning tumors, characterized by the secretion of pituitary hormones …

With the ageing of the global population, interest is growing in the 'geroscience hypothesis',
which posits that manipulation of fundamental ageing mechanisms will delay (in parallel) the …

Infertility is a disease characterized by the failure to establish a clinical pregnancy after 12
months of regular and unprotected sexual intercourse. It is estimated to affect between 8 and …

Pituitary-Tumor Endocrinopathies Pituitary adenomas account for about 15% of intracranial
tumors. Clinical manifestations of disease reflect the oversecretion of the involved hormone …

Importance Pituitary adenomas may hypersecrete hormones or cause mass effects.
Therefore, early diagnosis and treatment are important. Observations Prevalence of pituitary …

Background Pituitary tumours are common and easily treated by surgery or medical
treatment in most cases. However, a small subset of pituitary tumours does not respond to …

Acromegaly is a chronic systemic disease with many complications and is associated with
increased mortality when not adequately treated. Substantial advances in acromegaly …

Prolactinomas and nonfunctioning pituitary adenomas are the most frequent subtypes of
clinically relevant adenomas, followed by acromegaly and Cushing's disease. The incidence …

Acromegaly is a rare condition necessitating large population studies for the generation of
reliable epidemiological data. In this review, we systematically analysed the epidemiological …