Clinical utility of interleukin-1 inhibitors in pediatric sepsis

R Manchikalapati, J Schening, AJ Farias, KA Sacco - Shock, 2024 - journals.lww.com
The pathophysiology of pediatric sepsis is characterized by increased innate immune
activation earlier in life. Interleukin-1 is a proinflammatory cytokine implicated in the …

A decade of USFDA-approved small molecules as anti-inflammatory agents: Recent trends and Commentaries on the “industrial” perspective

V Mehta, AR Dwivedi, A Ludhiadch, V Rana… - European Journal of …, 2023 - Elsevier
Inflammation is the human body's defence process against various pathogens, toxic
substances, irradiation, and physically injured cells that have been damaged. Inflammation …

Anakinra authorized to treat severe coronavirus disease 2019; Sepsis breakthrough or time to reflect?

L Shapiro, S Scherger, C Franco-Paredes… - Frontiers in …, 2023 - frontiersin.org
Introduction The European Medicines Agency (EMA) and the United States Food and Drug
Administration (FDA) announced conditions for using recombinant human interleukin-1 …

COVID-19: An Update on the Latest Therapeutic Agents

KY Loo, LTH Tan, JWF Law, KW Hong… - Progress In Microbes …, 2023 - hh-publisher.com
The COVID-19 pandemic has plagued the world for over three years since discovering the
causative virus, SARS-CoV-2, in China. The rampant spread of the virus led to the loss of …

High expression of IL6 and decrease in immune cells in COVID-19 patients combined with myocardial injury

T Chen, H Chen, P Chen, L Zhu, W Mao… - Frontiers in …, 2023 - frontiersin.org
Purpose Myocardial injury, as a serious complication of coronavirus disease-2019 (COVID-
19), increases the occurrence of adverse outcomes. Identification of key regulatory …

Adverse drug reactions associated with COVID-19 management

V Chavda, P Dodiya, V Apostolopoulos - … -Schmiedeberg's Archives of …, 2024 - Springer
The emergence of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
outbreak, which causes COVID-19, had a devastating impact on both people's lives and the …

Navigating the Modern Landscape of Sepsis: Advances in Diagnosis and Treatment

JH Jang, E Choi, T Kim, HJ Yeo, D Jeon… - International Journal of …, 2024 - mdpi.com
Sepsis poses a significant threat to human health due to its high morbidity and mortality
rates worldwide. Traditional diagnostic methods for identifying sepsis or its causative …

Anakinra for the prophylaxis of venous thromboembolism in patients with COVID-19

CS Kow, DS Ramachandram, SS Hasan - Inflammopharmacology, 2023 - Springer
Bektaş et al.(2023), in a retrospective observational study, investigated the effect of high-
dose intravenous anakinra on the clinical outcomes in patients with severe and critically ill …

[PDF][PDF] Leki biologiczne w farmakoterapii dny moczanowej–aktualne możliwości i perspektywy na przyszłość

GK Jakubiak - researchgate.net
Dna moczanowa jest przewlekłą chorobą zapalną stawów, w której kluczowym zjawiskiem
patogenetycznym jest odpowiedź zapalna związana z obecnością kryształów moczanu …

[PDF][PDF] Curriculum vitae Europass

T Ortodoxă, D şi Misiune, F Duhovnicească - 2017 - cnatdcu.ro
Perioada▪ 20 aprilie 2016–prezent: Decan Facultatea de Teologie Ortodoxă, Universitatea
din Craiova.▪ 1 octombrie 2015–19 aprilie 2016: Director al Departamentului de Teologie …