Natural killer (NK) cells are lymphocytes that contribute to the early immune responses to
viruses. NK cells are innate immune cells that do not express rearranged antigen receptors …

Cytomegaloviruses (CMVs) are highly prevalent, persistent human pathogens that not only
evade but also shape our immune responses. Natural killer (NK) cells play an important role …

Infection by human cytomegalovirus (HCMV) leads to NKG2C-driven expansion of adaptive
natural killer (NK) cells, contributing to host defense. However, approximately 4% of all …

Major histocompatibility complex class I (MHC-I)-restricted immune responses are largely
attributed to cytotoxic T lymphocytes (CTLs). However, natural killer (NK) cells, as predicted …

Natural killer (NK) cells are innate lymphoid cells involved in the control of tumors and viral
infections. They provide protection by producing cytokines and by directly lysing target cells …

The continuous interactions between host and pathogens during their coevolution have
shaped both the immune system and the countermeasures used by pathogens. Natural killer …

Highlights•NK cells are lymphocytes that belong to innate arm of the immune system.•NK
cells are very important in resistance to many viruses and tumors.•Cytomegaloviruses are …

Natural killer (NK) cells play a key role in antiviral innate defenses because of their abilities
to kill infected cells and secrete regulatory cytokines. Additionally, NK cells exhibit adaptive …

Cytomegalovirus (CMV) causes clinically important diseases in immune compromised and
immune immature individuals. Based largely on work in the mouse model of murine (M) …

Highlights•NK cells protect by killing virus-infected cells and making IFN-γ.•Viruses evade
immunity by modulating NK-cell function.•NK cells can participate in and regulate long-lived …