Hantaviruses are a significant and emerging global public health threat, impacting more
than 200,000 individuals worldwide each year. The single-stranded RNA viruses belong to …

Neutralizing antibodies (NAbs) are naturally produced by our immune system to combat viral
infections. Clinically, neutralizing antibodies with potent efficacy and high specificity have …

Smallpox was a highly contagious disease caused by the variola virus. The disease affected
millions of people over thousands of years and variola virus ranked as one of the deadliest …

The Bunyavirales order includes at least fourteen families with diverse but related viruses,
which are transmitted to vertebrate hosts by arthropod or rodent vectors. These viruses are …

Identification of B-cell epitopes facilitates the development of vaccines, therapeutic
antibodies and diagnostic tools. Previously, the binding site of the bank vole monoclonal …

Orthohantaviruses may cause hemorrhagic fever with renal syndrome or hantavirus
cardiopulmonary syndrome. Andes virus (ANDV) is the only orthohantavirus associated with …

Crimean–Congo hemorrhagic fever virus (CCHFV) is a tick-borne virus that can cause
severe disease in humans with case fatality rates of 10–40%. Although structures of CCHFV …

Orthohantaviruses are emerging zoonotic viruses that can infect humans via the respiratory
tract. There is a clear unmet need for an in vivo model to study orthohantavirus infection in …