Characterization, antibacterial, and cytotoxic activities of silver nanoparticles using the whole biofilm layer as a macromolecule in biosynthesis

AY Yakoup, AG Kamel, Y Elbermawy… - Scientific Reports, 2024 - nature.com
Recently, multi-drug resistant (MDR) bacteria are responsible for a large number of
infectious diseases that can be life-threatening. Globally, new approaches are targeted to …

Bacteriophage therapy against ESKAPE bacterial pathogens: Current status, strategies, challenges, and future scope

M Kulshrestha, M Tiwari, V Tiwari - Microbial Pathogenesis, 2023 - Elsevier
The ESKAPE pathogens are the primary threat due to their constant spread of drug
resistance worldwide. These pathogens are also regarded as opportunistic pathogens and …

Phage therapy as a novel therapeutic for the treatment of bone and joint infections

GA Suh, T Ferry, MP Abdel - Clinical Infectious Diseases, 2023 - academic.oup.com
Solutions for bone and joint infection (BJI) are needed where conventional treatments are
inadequate. Bacteriophages (phages) are naturally occurring viruses that infect bacteria and …

Bacteriophage therapy to control bovine mastitis: A review

JY Nale, NR McEwan - Antibiotics, 2023 - mdpi.com
Bovine mastitis is a polymicrobial disease characterised by inflammation of the udders of
dairy and beef cattle. The infection has huge implications to health and welfare of animals …

How simple Maths can inform our Basic understanding of phage therapy

ST Abedon - Clinical Infectious Diseases, 2023 - academic.oup.com
Phage therapy is the application of bacterial viruses to control and, ideally, to eliminate
problematic bacteria from patients. Usually employed are so-called strictly lytic phages …

SpyPhage: a cell-free TXTL platform for rapid engineering of targeted phage therapies

SBW Liyanagedera, J Williams, JP Wheatley… - ACS Synthetic …, 2022 - ACS Publications
The past decade has seen the emergence of multidrug resistant pathogens as a leading
cause of death worldwide, reigniting interest in the field of phage therapy. Modern advances …

Development of Phage Cocktails to Treat E. coli Catheter-Associated Urinary Tract Infection and Associated Biofilms

BC Sanchez, ER Heckmann, SI Green… - Frontiers in …, 2022 - frontiersin.org
High rates of antimicrobial resistance and formation of biofilms makes treatment of
Escherichia coli catheter-associated urinary tract infections (CAUTI) particularly challenging …

Rapid assessment of changes in phage bioactivity using dynamic light scattering

T Dharmaraj, MJ Kratochvil, JD Pourtois, Q Chen… - PNAS …, 2023 - academic.oup.com
Extensive efforts are underway to develop bacteriophages as therapies against antibiotic-
resistant bacteria. However, these efforts are confounded by the instability of phage …

Phage therapy in a lung transplant recipient with cystic fibrosis infected with multidrug‐resistant Burkholderia multivorans

G Haidar, BK Chan, ST Cho… - Transplant Infectious …, 2023 - Wiley Online Library
Background There is increased interest in bacteriophage (phage) therapy to treat infections
caused by antibiotic‐resistant bacteria. A lung transplant recipient with cystic fibrosis and …

Genetic engineering and biosynthesis technology: Keys to unlocking the chains of phage therapy

S Lv, Y Wang, K Jiang, X Guo, J Zhang, F Zhou, Q Li… - Viruses, 2023 - mdpi.com
Phages possess the ability to selectively eliminate pathogenic bacteria by recognizing
bacterial surface receptors. Since their discovery, phages have been recognized for their …