Major tail proteins of bacteriophages of the order Caudovirales

M Zinke, GF Schröder, A Lange - Journal of Biological Chemistry, 2022 - ASBMB
Technological advances in cryo-EM in recent years have given rise to detailed atomic
structures of bacteriophage tail tubes—a class of filamentous protein assemblies that could …

Phage adsorption to gram-positive bacteria

A Leprince, J Mahillon - Viruses, 2023 - mdpi.com
The phage life cycle is a multi-stage process initiated by the recognition and attachment of
the virus to its bacterial host. This adsorption step depends on the specific interaction …

Systematic exploration of Escherichia coli phage–host interactions with the BASEL phage collection

E Maffei, A Shaidullina, M Burkolter, Y Heyer… - PLoS …, 2021 - journals.plos.org
Bacteriophages, the viruses infecting bacteria, hold great potential for the treatment of
multidrug-resistant bacterial infections and other applications due to their unparalleled …

Protein target highlights in CASP15: Analysis of models by structure providers

LT Alexander, J Durairaj… - Proteins: Structure …, 2023 - Wiley Online Library
We present an in‐depth analysis of selected CASP15 targets, focusing on their biological
and functional significance. The authors of the structures identify and discuss key protein …

Deciphering bacteriophage T5 host recognition mechanism and infection trigger

S Degroux, G Effantin, R Linares, G Schoehn… - Journal of …, 2023 - Am Soc Microbiol
Bacteriophages, viruses infecting bacteria, recognize their host with high specificity, binding
to either saccharide motifs or proteins of the cell wall of their host. In the majority of …

Present impact of AlphaFold2 revolution on structural biology, and an illustration with the structure prediction of the bacteriophage J-1 host adhesion device

A Goulet, C Cambillau - Frontiers in Molecular Biosciences, 2022 - frontiersin.org
In 2021, the release of AlphaFold2-the DeepMind's machine-learning protein structure
prediction program-revolutionized structural biology. Results of the CASP14 contest were an …

Tall tails: cryo-electron microscopy of phage tail DNA ejection conduits

JM Hardy, RA Dunstan, T Lithgow… - Biochemical Society …, 2022 - portlandpress.com
The majority of phages, viruses that infect prokaryotes, inject their genomic material into their
host through a tubular assembly known as a tail. Despite the genomic diversity of tailed …

Distantly related Alteromonas bacteriophages share tail fibers exhibiting properties of transient chaperone caps

R Gonzalez-Serrano, R Rosselli… - Nature …, 2023 - nature.com
The host recognition modules encoding the injection machinery and receptor binding
proteins (RBPs) of bacteriophages are predisposed to mutation and recombination to …

Isolation and Characterization of a Novel Siphoviridae Phage, vB_AbaS_TCUP2199, Infecting Multidrug-Resistant Acinetobacter baumannii

M Mardiana, SH Teh, LC Lin, NT Lin - Viruses, 2022 - mdpi.com
Multidrug-resistant Acinetobacter baumannii (MDRAB) is a pathogen recognized as
antimicrobial-resistant bacteria involved in healthcare-associated infections. Resistance to …

Structure and Topology Prediction of Phage Adhesion Devices Using AlphaFold2: The Case of Two Oenococcus oeni Phages

A Goulet, C Cambillau - Microorganisms, 2021 - mdpi.com
Lactic acid bacteria (LAB) are important microorganisms in food fermentation. In the food
industry, bacteriophages (phages or bacterial viruses) may cause the disruption of LAB …