Type 2 diabetes

E Ahmad, S Lim, R Lamptey, DR Webb, MJ Davies - The Lancet, 2022 - thelancet.com
Type 2 diabetes accounts for nearly 90% of the approximately 537 million cases of diabetes
worldwide. The number affected is increasing rapidly with alarming trends in children and …

The amyloid-β pathway in Alzheimer's disease

H Hampel, J Hardy, K Blennow, C Chen, G Perry… - Molecular …, 2021 - nature.com
Breakthroughs in molecular medicine have positioned the amyloid-β (Aβ) pathway at the
center of Alzheimer's disease (AD) pathophysiology. While the detailed molecular …

[PDF][PDF] Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2

M Reiterer, M Rajan, N Gómez-Banoy, JD Lau… - Cell metabolism, 2021 - cell.com
Individuals infected with SARS-CoV-2 who also display hyperglycemia suffer from longer
hospital stays, higher risk of developing acute respiratory distress syndrome (ARDS), and …

[PDF][PDF] Diabetes, obesity, metabolism, and SARS-CoV-2 infection: the end of the beginning

DJ Drucker - Cell metabolism, 2021 - cell.com
The increased prevalence of obesity, diabetes, and cardiovascular risk factors in people
hospitalized with severe COVID-19 illness has engendered considerable interest in the …

ECMM/ISHAM recommendations for clinical management of COVID‐19 associated mucormycosis in low‐and middle‐income countries

SM Rudramurthy, M Hoenigl, JF Meis, OA Cornely… - Mycoses, 2021 - Wiley Online Library
Reports are increasing on the emergence of COVID‐19–associated mucormycosis (CAM)
globally, driven particularly by low‐and middle‐income countries. The recent unprecedented …

Cardiovascular disease and COVID-19: a consensus paper from the ESC working group on coronary pathophysiology & microcirculation, ESC working group on …

E Cenko, L Badimon, R Bugiardini… - Cardiovascular …, 2021 - academic.oup.com
The cardiovascular system is significantly affected in coronavirus disease-19 (COVID-19).
Microvascular injury, endothelial dysfunction, and thrombosis resulting from viral infection or …

Tirzepatide, a new era of dual-targeted treatment for diabetes and obesity: a mini-review

VP Chavda, J Ajabiya, D Teli, J Bojarska… - Molecules, 2022 - mdpi.com
The prevalence of obesity and diabetes is an increasing global problem, especially in
developed countries, and is referred to as the twin epidemics. As such, advanced treatment …

[HTML][HTML] Diabetes fact sheet in Korea 2021

JH Bae, KD Han, SH Ko, YS Yang, JH Choi… - … & Metabolism Journal, 2022 - ncbi.nlm.nih.gov
Background This study aimed to investigate the prevalence and management of diabetes
mellitus, risk-factor control, and comorbidities among Korean adults. Methods We conducted …

Nitric oxide signalling in kidney regulation and cardiometabolic health

M Carlström - Nature reviews nephrology, 2021 - nature.com
The prevalence of cardiovascular and metabolic disease coupled with kidney dysfunction is
increasing worldwide. This triad of disorders is associated with considerable morbidity and …

Fresh insights into glucocorticoid-induced diabetes mellitus and new therapeutic directions

JX Li, CL Cummins - Nature Reviews Endocrinology, 2022 - nature.com
Glucocorticoid hormones were discovered to have use as potent anti-inflammatory and
immunosuppressive therapeutics in the 1940s and their continued use and development …