[HTML][HTML] Generation of somatic de novo structural variation as a hallmark of cellular senescence in human lung fibroblasts

V Woronzow, J Möhner, D Remane… - Frontiers in Cell and …, 2023 - ncbi.nlm.nih.gov
Cellular senescence is characterized by replication arrest in response to stress stimuli.
Senescent cells accumulate in aging tissues and can trigger organ-specific and possibly …

Genome instability and somatic retropositional mosaicism in the adult human brain

J Möhner - 2023 - openscience.ub.uni-mainz.de
Zellen des Somas, insbesondere des Gehirns, bilden regionenspezifisch unterschiedlich
häufig genomische Variationen aus, was zu einem somatischen Mosaizismus führt. Dieses …