The role of autophagy in cardiovascular disease: Cross-interference of signaling pathways and underlying therapeutic targets

B Jiang, X Zhou, T Yang, L Wang, L Feng… - Frontiers in …, 2023 - frontiersin.org
Autophagy is a conserved lysosomal pathway for the degradation of cytoplasmic proteins
and organelles, which realizes the metabolic needs of cells and the renewal of organelles …

Inhibition of myocardial cell apoptosis is important mechanism for ginsenoside in the limitation of myocardial ischemia/reperfusion injury

Z Chen, J Wu, S Li, C Liu, Y Ren - Frontiers in Pharmacology, 2022 - frontiersin.org
Ischemic heart disease has a high mortality, and the recommended therapy is reperfusion.
Nevertheless, the restoration of blood flow to ischemic tissue leads to further damage …

Chinese traditional formula Kaixin San suppressed ferroptosis of hippocampal neurons and cardiomyocytes in mice with paradoxical sleep deprivation

Y Cao, M Li, L Gu, X Zhao, A Zhou, Y Miao, Y Wu… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Kaixin San (KXS) is one of the most famous traditional
Chinese formulas prescribed by Sun Simiao in 652 Christian era. It is composed of Panax …

Role of curcumin in ischemia and reperfusion injury

M Bi, D Li, J Zhang - Frontiers in Pharmacology, 2023 - frontiersin.org
Ischemia-reperfusion injury (IRI) is an inevitable pathological process after organic
transplantations. Although traditional treatments restore the blood supply of ischemic …

Chronic sleep deprivation impaired bone formation in growing rats and down-regulated PI3K/AKT signaling in bone tissues

X Duan, Q Pan, L Guo - Nature and Science of Sleep, 2022 - Taylor & Francis
Background This study aimed to assess the effects of chronic sleep deprivation (CSD) on
bone metabolism in growing rats and the likely underlying mechanism. Methods Twenty 5 …

[HTML][HTML] YT521-B homology domain containing 1 ameliorates mitochondrial damage and ferroptosis in sleep deprivation by activating the sirtuin 1/nuclear factor …

J Chen, L Xiao, Y Chen, W Li, Y Liu, Y Zhou… - Brain Research Bulletin, 2023 - Elsevier
In sleep deprivation (SD) models, ferroptosis is increased. SIRT1 alleviates cognitive
impairment in SD, and SIRT1/NRF2/HO1 pathway depresses ferroptosis in different …

Establishment of a chronic insomnia rat model of sleep fragmentation using unstable platforms surrounded by water

DQ Yan, XP Zhang, WH Zhang… - Experimental and …, 2023 - spandidos-publications.com
Chronic fragmented sleep is a very common type of insomnia that affects the daily lives of
numerous people around the world. However, its pathogenesis is not very clear and a …

[HTML][HTML] Ginseng and ginsenosides on cardiovascular and pulmonary diseases; Pharmacological potentials for the coronavirus (COVID-19)

A Vijayakumar, JH Kim - Journal of Ginseng Research, 2023 - Elsevier
Since its outbreak in late 2019, the Coronavirus disease 2019 (COVID-19) pandemic has
profoundly caused global morbidity and deaths. The COVID-19 pandemic caused by Severe …

An instant beverage rich in nutrients and secondary metabolites manufactured from stems and leaves of Panax notoginseng

Z Liang, K Liu, R Li, B Ma, W Zheng, S Yang… - Frontiers in …, 2022 - frontiersin.org
Introduction Radix Notoginseng, one of the most famous Chinese traditional medicines, is
the dried root of Panax notoginseng (Araliaceae). Stems and leaves of P. notoginseng …

Study on Chemical Constituents of Panax notoginseng Leaves

X Sun, H Deng, T Shu, M Xu, L Su, H Li - Molecules, 2023 - mdpi.com
Panax notoginseng (Burk.) FH is a genuine medicinal material in Yunnan Province. As
accessories, P. notoginseng leaves mainly contain protopanaxadiol saponins. The …