Roles of circular RNAs in immune regulation and autoimmune diseases

Z Zhou, B Sun, S Huang, L Zhao - Cell death & disease, 2019 - nature.com
Circular RNAs (circRNAs), as a novel class of endogenously expressed non-coding RNAs
(ncRNAs), have a high stability and often present tissue-specific expression and …

Signaling pathways and targeted therapies for psoriasis

J Guo, H Zhang, W Lin, L Lu, J Su… - Signal Transduction and …, 2023 - nature.com
Psoriasis is a common, chronic, and inflammatory skin disease with a high burden on
individuals, health systems, and society worldwide. With the immunological pathologies and …

The N6-methyladenosine modification of circALG1 promotes the metastasis of colorectal cancer mediated by the miR-342-5p/PGF signalling pathway

C Lin, M Ma, Y Zhang, L Li, F Long, C Xie, H Xiao… - Molecular cancer, 2022 - Springer
Background Previous studies have shown that the N6-methyladenosine (m6A) modification
enhances the binding ability of mRNAs/long noncoding RNAs (lncRNAs) to microRNAs …

Genetic and Epigenetic Mechanisms of Psoriasis

L Mateu-Arrom, L Puig - Genes, 2023 - mdpi.com
Psoriasis is a disease involving the innate and adaptative components of the immune
system, and it is triggered by environmental factors in genetically susceptible individuals …

Transcriptome profiling analyses in psoriasis: a dynamic contribution of keratinocytes to the pathogenesis

G Rioux, Z Ridha, M Simard, F Turgeon, SL Guérin… - Genes, 2020 - mdpi.com
Psoriasis is an immune-mediated inflammatory skin disease with a complex etiology
involving environmental and genetic factors. A better insight into related genomic alteration …

Emerging roles of non-coding RNAs in psoriasis pathogenesis

D Ghosh, T Ganguly, R Chatterjee - Functional & Integrative Genomics, 2023 - Springer
Psoriasis is a complex genetic skin disorder typically manifested by red, scaly, and itchy
plaques most commonly over the scalp, trunk, elbows, and knees. Histopathological features …

[HTML][HTML] Circular RNA: A novel potential biomarker for skin diseases

X Wu, Y Xiao, J Ma, A Wang - Pharmacological research, 2020 - Elsevier
Circular RNA (circRNA) has been classified as noncoding RNA with a covalent closed
continuous loop, the 3′ and 5′ ends of which are normally joined together to increase its …

[HTML][HTML] Non-coding RNAs in immunoregulation and autoimmunity: Technological advances and critical limitations

D Kumar, SS Sahoo, D Chauss, M Kazemian… - Journal of …, 2023 - Elsevier
Immune cell function is critically dependent on precise control over transcriptional output
from the genome. In this respect, integration of environmental signals that regulate gene …

circRNA: regulatory factors and potential therapeutic targets in inflammatory dermatoses

R Liu, L Zhang, X Zhao, J Liu, W Chang… - Journal of cellular …, 2022 - Wiley Online Library
The skin is the largest organ of the human body and acts as the first line of defence against
injury and infection. Skin diseases are among the most common health problems and are …

Dysregulated circRNA_100876 suppresses proliferation of osteosarcoma cancer cells by targeting microRNA‐136

J Jin, A Chen, W Qiu, Y Chen, Q Li… - Journal of cellular …, 2019 - Wiley Online Library
The aim of this study was to explore the regulatory mechanism of circRNA_100876/
microRNA‐136 (miR‐136) axis in the development and progression of osteosarcoma …