Background Preeclampsia (PE) is associated with subsequent higher risk of cardiovascular
and kidney disease. Serum copeptin, as a proxy for vasopressin, and urinary uromodulin …

Background The progression of chronic kidney disease (CKD), a global public health
burden, is accompanied by a declining number of functional nephrons. Estimation of …

Background Children who require surgery for congenital heart disease have increased risk
for long-term chronic kidney disease (CKD). Clinical factors as well as urine biomarkers of …

Acute kidney injury (AKI) is a common complication in hospitalized patients with cirrhosis.
Uromodulin, a protein uniquely produced by the kidney and released both in the urine and …

Simple Summary Simple Summary: Uromodulin has been known for many years as a
normal protein component of urine. However, in recent years, serum as well as urinary …

Uromodulin is a nephrospecific protein that is most common in normal urine. And although it
has been known for more than 70 years, the function of uromodulin remains unclear …

Uromodulin, the most abundant protein in urine, is synthesized in the thick ascending loop of
Henle and distal convoluted tubules. Patients with chronic kidney disease (CKD) have …

Background Acute kidney injury (AKI) is a major complication following cardiac surgery that
substantially increases mortality. We explored the clinical utility of urinary uromodulin …

Uromodulin is exclusively expressed and secreted by cells of the ascending limb of the loop
of Henle and the distal tubule into the urine and the bloodstream and is hypothesized to be a …

Sir,–Uromodulin, also known as Tamm-Horsfall-protein is an~ 95 kDa large molecule
exclusively produced in the ascending limb in the loop of Henle and in the distal tubule [1] …