Heterotopic ossification: basic-science principles and clinical correlates

K Ranganathan, S Loder, S Agarwal, VW Wong… - JBJS, 2015 - journals.lww.com
Heterotopic ossification is the formation of ectopic lamellar bone in soft tissues. It is
increasingly recognized as a complication following trauma, burns, neurologic injuries, and …

Multiple organ dysfunction and systemic inflammation after spinal cord injury: a complex relationship

X Sun, ZB Jones, X Chen, L Zhou, KF So… - Journal of …, 2016 - Springer
Spinal cord injury (SCI) is a devastating event that results in significant physical disabilities
for affected individuals. Apart from local injury within the spinal cord, SCI patients develop a …

Neurological heterotopic ossification following spinal cord injury is triggered by macrophage‐mediated inflammation in muscle

F Genêt, I Kulina, C Vaquette, F Torossian… - The Journal of …, 2015 - Wiley Online Library
Neurological heterotopic ossification (NHO) is the abnormal formation of bone in soft tissues
as a consequence of spinal cord or traumatic brain injury. NHO causes pain, ankyloses …

Heterotopic ossification in orthopaedic trauma

A Nauth, E Giles, BK Potter, LJ Nesti… - … of orthopaedic trauma, 2012 - journals.lww.com
Heterotopic ossification (HO) can be defined as the pathologic formation of bone in
extraskeletal tissues. There has been a substantial amount of recent research on the …

[HTML][HTML] Heterotopic ossification in COVID-19: a series of 4 cases

C Meyer, MA Haustrate, JF Nisolle… - Annals of physical and …, 2020 - ncbi.nlm.nih.gov
Heterotopic ossification (HO) refers to abnormal formation of mature lamellar bone in soft
tissues without connection to the periosteum, around proximal articulations, knees and …

Challenges of heterotopic ossification—molecular background and current treatment strategies

P Łęgosz, K Drela, Ł Pulik… - Clinical and …, 2018 - Wiley Online Library
Heterotopic ossification (HO) is an abnormal formation of mature lamellar bone within
extraskeletal soft tissues, such as muscles, tendons, and ligaments. This process is thought …

Heterotopic ossification after trauma

J Lawand, Z Loeffelholz, B Khurshid… - Orthopedic …, 2023 - orthopedic.theclinics.com
Recommendations regarding the timing of surgical intervention are variable, with some
studies recommending against waiting for lesion maturation of the heterotopically ossified …

Extensive progressive heterotopic ossification post-Covid-19 in a man

ML Brance, NM Coccaro, AN Casalongue, A Duran… - Bone, 2022 - Elsevier
Heterotopic ossification (HO) is the formation of extraskeletal bone in muscle and soft tissues
and could be genetic or non-genetic. The classic presentation of non-genetic HO is in young …

When the nervous system turns skeletal muscles into bones: how to solve the conundrum of neurogenic heterotopic ossification

KA Alexander, HW Tseng, M Salga, F Genêt… - Current osteoporosis …, 2020 - Springer
Abstract Purpose of Review Neurogenic heterotopic ossification (NHO) is the abnormal
formation of extra-skeletal bones in periarticular muscles after damage to the central …

[HTML][HTML] Recurrence of heterotopic ossification after removal in patients with traumatic brain injury: a systematic review

W Almangour, A Schnitzler, M Salga, C Debaud… - Annals of physical and …, 2016 - Elsevier
Objective A systematic review of the literature to determine whether in patients with
neurological heterotopic ossification (NHO) after traumatic brain injury, the extent of the …