Atherosclerotic cardiovascular disease (ASCVD) is epidemic throughout the world and is
etiologic for such acute cardiovascular events as myocardial infarction, ischemic stroke …

The treatment of dyslipidemia continues to be a dynamic and controversial topic. Even the
most appropriate therapeutic range for lipid levels—including that of triglycerides and low …

Background Randomized clinical trials (RCTs) might not be representative of the real‐world
population because of unreasonable exclusion criteria. We sought to determine which …

Background Previous prediction algorithms for cardiovascular diseases (CVD) were
established using risk factors retrieved largely based on empirical clinical knowledge. This …

Importance Statin use is common in older persons. Given uncertainties in ongoing benefit,
changes in health status, and shifting goals of care and preferences, statin discontinuation …

Background The effectiveness of lipid‐lowering therapy (LLT) is affected by both intensity
and adherence. This study evaluated the associations of LLT intensity, adherence, and the …

Background potentially harmful polypharmacy is very common in older people living in aged
care facilities. To date, there have been no double-blind randomised controlled studies of …

This review will discuss the limitations of data collected by RCTs in relation to their
applicability to daily life clinical management. It will then argue that these limitations are only …

Heart failure (HF) is associated with morbidity, rehospitalization and polypharmacy. The
incidence rate of mortality in HF patients with polypharmacy is poorly studied. We examine …

Primary prevention statin therapy in older adults : Current Opinion in Cardiology Primary
prevention statin therapy in older adults : Current Opinion in Cardiology Log in or Register …