Background There are observational data suggesting an inverse association between
circulating concentrations of sex hormone binding globulin (SHBG) and risk of …

Introduction Male hypogonadism is a common condition, with an increasing body of
literature on diagnosis, implications, and management. Given the significant variability in …

Background Although clinicians often measure the serum concentration of androgens in
premenopausal women presenting with sexual dysfunction, with some women given …

Aims/hypothesis Serum sex hormone-binding globulin (SHBG) has been proposed to act as
a hepatokine that contributes to the extrahepatic complications observed in non-alcoholic …

BACKGROUND In recent years it became evident that several types of the luteinizing
hormone/choriogonadotrophin receptor (LHCGR) exist. In addition to the classical receptor …

Background The chromodomain helicase DNA binding domain (CHD) proteins modulate
gene expression via their ability to remodel chromatin structure and influence histone …

Mapping expression quantitative trait loci (eQTLs) has been shown as a powerful tool to
uncover the genetic underpinnings of many complex traits at molecular level. In this paper …

Vascular endothelial growth factor (VEGF) is an angiogenic and neurotrophic factor,
secreted by endothelial cells, known to impact various physiological and disease processes …

Background Testosterone supplementation has been linked to increased cardiovascular
disease risk in some observational studies. The causal role of testosterone can be …

The ratio of the length of the index finger to that of the ring finger (2D: 4D) is sexually
dimorphic and is commonly used as a non-invasive biomarker of prenatal androgen …