[HTML][HTML] Preventing peritoneal membrane fibrosis in peritoneal dialysis patients

Q Zhou, MA Bajo, G Del Peso, X Yu, R Selgas - Kidney international, 2016 - Elsevier
Long-term peritoneal dialysis causes morphologic and functional changes in the peritoneal
membrane. Although mesothelial-mesenchymal transition of peritoneal mesothelial cells is a …

Molecular pathways in peritoneal fibrosis

MS Balzer - Cellular signalling, 2020 - Elsevier
Peritoneal dialysis (PD) is a renal replacement therapy for patients with end-stage renal
disease that is equivalent to hemodialysis with respect to adequacy, mortality, and other …

[HTML][HTML] Fibrosis of peritoneal membrane as target of new therapies in peritoneal dialysis

V Masola, M Bonomini, S Borrelli, L Di Liberato… - International journal of …, 2022 - mdpi.com
Peritoneal dialysis (PD) is an efficient renal replacement therapy for patients with end-stage
renal disease. Even if it ensures an outcome equivalent to hemodialysis and a better quality …

Curcumin protects against hyperosmoticity-induced IL-1β elevation in human corneal epithelial cell via MAPK pathways

M Chen, DN Hu, Z Pan, CW Lu, CY Xue… - Experimental eye …, 2010 - Elsevier
Increased tear osmolarity is an essential feature of dry eye disease. Curcumin, a natural
polyphenol extracted from herb turmeric, has recently been reported to have anti …

[HTML][HTML] Autophagy in peritoneal fibrosis

H Su, J Yang, R Zou, N An, X Chen, C Yang… - Frontiers in …, 2023 - frontiersin.org
Peritoneal dialysis (PD) is a widely accepted renal replacement therapy for patients with end-
stage renal disease (ESRD). Morphological and functional changes occur in the peritoneal …

Inhibition of EGF receptor blocks the development and progression of peritoneal fibrosis

L Wang, N Liu, C Xiong, L Xu, Y Shi, A Qiu… - Journal of the …, 2016 - journals.lww.com
Inhibitors of EGF receptor (EGFR) have antifibrotic effects in several organs, but the effect of
these inhibitors on the development of peritoneal fibrosis is unknown. Here, we explored the …

Hypertonicity-induced expression of monocyte chemoattractant protein-1 through a novel cis-acting element and MAPK signaling pathways

R Kojima, H Taniguchi, A Tsuzuki… - The Journal of …, 2010 - journals.aai.org
MCP1 is upregulated by various stimuli, including LPS, high glucose, and hyperosmolality.
However, the molecular mechanisms of transcriptional regulation of the MCP1 gene under …

[HTML][HTML] Protein kinase C α inhibition prevents peritoneal damage in a mouse model of chronic peritoneal exposure to high-glucose dialysate

L Wang, MS Balzer, S Rong, J Menne… - Kidney International, 2016 - Elsevier
Chronic exposure to commercial glucose-based peritoneal dialysis fluids during peritoneal
dialysis induces peritoneal membrane damage leading to ultrafiltration failure. In this study …

[HTML][HTML] Activation of MAPK signaling pathway and NF-κB activation in pterygium and ipsilateral pterygium-free conjunctival specimens

J Torres, A Enríquez-de-Salamanca… - … & visual science, 2011 - iovs.arvojournals.org
Purpose.: To evaluate mitogen-activated protein kinases (MAPKs) and nuclear factor-κB (NF-
κB) signaling pathways in pterygium and pterygium-free conjunctivas. Methods.: Primary …

[HTML][HTML] Update on potential medical treatments for encapsulating peritoneal sclerosis; human and experimental data

T Cornelis, DG Oreopoulos - International urology and nephrology, 2011 - Springer
Encapsulating peritoneal sclerosis (EPS) is an infrequent but serious complication of
peritoneal dialysis (PD). The pathogenesis is unknown but speculation is ongoing. The …