Abstract MicroRNAs (miRNAs), small non-coding RNAs, can regulate post-transcriptional
gene expressions and silence a broad set of target genes. miRNAs, aberrantly expressed in …

The interplay between abnormalities in genes coding for proteins and noncoding
microRNAs (miRNAs) has been among the most exciting yet unexpected discoveries in …

Chemotherapeutic agents have certain limitations when it comes to treating cancer, the most
important being severe side effects along with multidrug resistance developed against them …

Ovarian cancer (OC) is the sixth most common cancer in women globally. However, even
with the advances in detection and therapeutics it still represents the most dangerous …

One of the most fascinating discoveries in molecular oncology has been that cancer
represents a disease in which genetic alterations in protein-coding, but also in non-coding …

Nanomedicine is a growing research field dealing with the creation and manipulation of
materials at a nanometer scale for the better treatment, diagnosis and imaging of diseases …

A growing body of evidence has indicated that long non-coding RNAs (lncRNAs) serve as
competing endogenous RNAs (ceRNAs) during oncogenesis. In this study, the qRT-PCR …

MicroRNA-21 is overexpressed in most cancers and has been implicated in tumorigenesis.
Accumulating evidence supports a central role for the miR-21 guide strand (miR-21-5p) in …

Ovarian cancer has the highest mortality rate among gynecological cancers. Early clinical
signs are missing and there is an urgent need to establish early diagnosis biomarkers …

Cisplatin has been the most accepted drug for the treatment of ovarian cancer for almost 40
years. Although the majority of patients with ovarian cancer respond to front-line platinum …