[HTML][HTML] Pathogenic mechanisms of post-acute sequelae of SARS-CoV-2 infection (PASC)

ZA Sherif, CR Gomez, TJ Connors, TJ Henrich… - Elife, 2023 - elifesciences.org
COVID-19, with persistent and new onset of symptoms such as fatigue, post-exertional
malaise, and cognitive dysfunction that last for months and impact everyday functioning, is …

[HTML][HTML] Immune mechanisms underlying COVID-19 pathology and post-acute sequelae of SARS-CoV-2 infection (PASC)

S Mohandas, P Jagannathan, TJ Henrich, ZA Sherif… - Elife, 2023 - elifesciences.org
With a global tally of more than 500 million cases of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infections to date, there are growing concerns about the post …

SARS-CoV-2 infection and recovery in children: Distinct T cell responses in MIS-C compared to COVID-19

K Rybkina, JN Bell, MC Bradley, T Wohlbold… - Journal of Experimental …, 2023 - rupress.org
SARS-CoV-2 infection for most children results in mild or minimal symptoms, though in rare
cases severe disease can develop, including a multisystem inflammatory syndrome (MIS-C) …

Liquid biomarkers of macrophage dysregulation and circulating spike protein illustrate the biological heterogeneity in patients with post‐acute sequelae of COVID‐19

C Schultheiß, E Willscher, L Paschold… - Journal of Medical …, 2023 - Wiley Online Library
Post‐acute sequelae of COVID‐19 (PASC) are long‐term consequences of SARS‐CoV‐2
infection that can substantially impair the quality of life. Underlying mechanisms ranging …

[HTML][HTML] COVID-19 heart lesions in children: clinical, diagnostic and immunological changes

E Vasichkina, D Alekseeva, I Kudryavtsev… - International Journal of …, 2023 - mdpi.com
In the beginning of COVID-19, the proportion of confirmed cases in the pediatric population
was relatively small and there was an opinion that children often had a mild or asymptomatic …

[HTML][HTML] Neutrophil profiles of pediatric COVID-19 and multisystem inflammatory syndrome in children

BP Boribong, TJ LaSalle, YC Bartsch, F Ellett… - Cell Reports …, 2022 - cell.com
Multisystem inflammatory syndrome in children (MIS-C) is a delayed-onset, COVID-19-
related hyperinflammatory illness characterized by severe acute respiratory syndrome …

[HTML][HTML] Immunological imprinting of humoral immunity to SARS-CoV-2 in children

AC Dowell, T Lancaster, R Bruton, G Ireland… - Nature …, 2023 - nature.com
Omicron variants of SARS-CoV-2 are globally dominant and infection rates are very high in
children. We measure immune responses following Omicron BA. 1/2 infection in children …

A cursed goodbye kiss from severe acute respiratory syndrome-coronavirus-2 to its pediatric hosts: multisystem inflammatory syndrome in children

F Haslak, A Gunalp, O Kasapcopur - Current Opinion in …, 2023 - journals.lww.com
Although children are likely to have a milder COVID-19 course compared with adults, MIS-C
as a postinfectious and life-threatening complication was reported in the pediatric age. After …

[HTML][HTML] Immunology of multisystem inflammatory syndrome after COVID-19 in children: a review of the current evidence

F Filippatos, EB Tatsi, A Michos - International Journal of Molecular …, 2023 - mdpi.com
Immune responses following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) in children are still under investigation. Even though coronavirus disease 2019 (COVID …

[HTML][HTML] Antibody response in children with multisystem inflammatory syndrome related to COVID-19 (MIS-C) compared to children with uncomplicated COVID-19

A Thiriard, B Meyer, CS Eberhardt, N Loevy… - Frontiers in …, 2023 - frontiersin.org
Objectives To comprehensively analyze the quality of the antibody response between
children with Multisystem inflammatory syndrome (MIS-C) and age-matched controls at one …