[HTML][HTML] Mapping the genetic architecture of cortical morphology through neuroimaging: progress and perspectives

D van der Meer, T Kaufmann - Translational Psychiatry, 2022 - nature.com
Cortical morphology is a key determinant of cognitive ability and mental health. Its
development is a highly intricate process spanning decades, involving the coordinated …

Exploring the genetic overlap between twelve psychiatric disorders

C Romero, J Werme, PR Jansen, J Gelernter… - Nature …, 2022 - nature.com
The widespread comorbidity among psychiatric disorders demonstrated in epidemiological
studies–is mirrored by non-zero, positive genetic correlations from large-scale genetic …

Examining the shared etiology of psychopathology with genome-wide association studies

TT Mallard, AD Grotzinger… - Physiological …, 2023 - journals.physiology.org
Genome-wide association studies (GWASs) have ushered in a new era of reproducible
discovery in psychiatric genetics. The field has now identified hundreds of common genetic …

Heart-brain connections: Phenotypic and genetic insights from magnetic resonance images

B Zhao, T Li, Z Fan, Y Yang, J Shu, X Yang, X Wang… - Science, 2023 - science.org
Cardiovascular health interacts with cognitive and mental health in complex ways, yet little is
known about the phenotypic and genetic links of heart-brain systems. We quantified heart …

[HTML][HTML] The genetic architecture of pneumonia susceptibility implicates mucin biology and a relationship with psychiatric illness

WR Reay, MP Geaghan, MJ Cairns - Nature Communications, 2022 - nature.com
Pneumonia remains one of the leading causes of death worldwide. In this study, we use
genome-wide meta-analysis of lifetime pneumonia diagnosis (N= 391,044) to identify four …

Exploring the Genetic Link Between Thyroid Dysfunction and Common Psychiatric Disorders: A Specific Hormonal or a General Autoimmune Comorbidity

S Soheili-Nezhad, E Sprooten, I Tendolkar, M Medici - Thyroid, 2023 - liebertpub.com
Background: The hypothalamus-pituitary-thyroid axis coordinates brain development and
postdevelopmental function. Thyroid hormone (TH) variations, even within the normal range …

[HTML][HTML] Cross-disorder genetic analysis of immune diseases reveals distinct gene associations that converge on common pathways

P Demela, N Pirastu, B Soskic - Nature Communications, 2023 - nature.com
Cross-disorder genetic analysis of immune diseases reveals distinct gene associations that
converge on common pathways | Nature Communications Skip to main content Thank you for …

The genetic architectures of functional and structural connectivity properties within cerebral resting-state networks

E Tissink, J Werme, SC de Lange, JE Savage, Y Wei… - Eneuro, 2023 - eneuro.org
Functional connectivity within resting-state networks (RSN-FC) is vital for cognitive
functioning. RSN-FC is heritable and partially translates to the anatomic architecture of white …

[HTML][HTML] A genomic assessment of the correlation between milk production traits and claw and udder health traits in Holstein dairy cattle

H Schneider, D Segelke, J Tetens, G Thaller… - Journal of Dairy …, 2023 - Elsevier
Claw diseases and mastitis represent the most important disease traits in dairy cattle with
increasing incidences and a frequently mentioned connection to milk yield. Yet, many …

[HTML][HTML] Association between genetically proxied PCSK9 inhibition and prostate cancer risk: A Mendelian randomisation study

S Fang, J Yarmolinsky, D Gill, CJ Bull, CM Perks… - Plos …, 2023 - journals.plos.org
Background Prostate cancer (PrCa) is the second most prevalent malignancy in men
worldwide. Observational studies have linked the use of low-density lipoprotein cholesterol …